The Leverage team attempts to expose a conglomerate’s cover-up of their toxic fertilizer, which has resulted in the death of a young girl. But the CEO has put all of the damning evidence on a plane to the Cayman Islands. The team races to catch the flight but, once airborne, they discover that the CEO’s intentions are far more sinister and that to avenge one life they’ll have to save their own.
Jim Sterling asks Nate for help taking down a researcher who has designed a nuclear weight that will allow a terrorist nation to manufacture enriched uranium. However, it soon becomes clear that the Interpol agent has an ulterior motive, one which isolates Nate, gets Sophie arrested, and takes Eliot out of commission.
With the other three team members still in Washington, Sophie sneaks off (soon followed by Nate) to the mansion of a recently deceased art collector, where a mysterious painting by a modern master will be publicly shown for the first time. When the painting turns up missing, Sophie and Nate must help Sterling solve a classic mystery to stop him from pinning the crime on them.