The animal attacks continue and the team discovers that the mutation has advanced further... rendering their cure ineffective. Now with the aid of an anonymous sponsor, the team head to Argentina to meet with a scientist who may have discovered the key to the mutation.
While Jamie tries to make her way to safety, an increasingly desperate Chloe tries to find a cure to the mutation now that one of her teammates is infected.
After tragedy strikes their only ally within the government, the team is left on their own to stop a surge of animal-related attacks from destroying the city of Geneva, Switzerland. Also, new team member Dariela makes a shocking discovery about General Davies, head of the Noah Objective, and in the Canadian wilderness, Jamie witnesses the animals’ broadening effect on the environment and uncovers a troubling detail about Logan.
In an effort to unravel a dark conspiracy within the Noah Objective, the team travels to Vancouver, where it must infiltrate a black-tie event in order to get close to General Davies and stave off an impending animal threat. Also, Jamie and Logan’s journey is interrupted when Logan’s past comes back to haunt them.
Jamie and Logan arrive in Caraquet but are horrified to find it’s not the refuge they hope for. Also, after the team gets a lead on Jamie’s location, they eagerly head to Caraquet in the hopes of reuniting with her.
The team travels to Portugal where they square off against a dangerous venom dealer in order to get one step closer to the cure. Also, Jackson's increasingly erratic behavior jeopardizes the entire team.
Mitch digs into Jackson’s past to get the answers they need to make the cure. Also, the rest of the team hunts for evidence related to the triple helix inside a quaint English town.
Jackson learns his mother is missing in Africa, but before he can look for her, he and the team must contend with a hostile force that has overtaken their plane. Also, Jamie learns a shocking secret about Abraham.
Jackson faces the most difficult decision of his life. Also, Mitch reluctantly enlists help from his father, Max Morgan, to investigate the origin of the final set of triple helix animal bones.
With Jackson missing, Mitch and Abraham race to find him before General Davies and the International Animal Defense Group can locate him and prevent the team from making a cure. Also, Jamie, Dariela and Allison make a last-ditch effort to convince the Russian government to drop out of the Noah Objective.
Mitch and Jamie brave an animal attack at the Russian Embassy in Washington, D.C., and Jackson finally gets the answers he’s been looking for from a surprising source.
Mitch and Jamie hatch a daring plan to undermine the Noah Objective once and for all, and the team reunites on the Island of Pangaea where the final pieces of the cure are put in place.
After escaping from a prison on Pangea, the team learns the truth about the triple spiral animals. A sacrifice and a devastating revelation change everything.
It has been 10 years since mankind was sterilized. Along the West Coast, a huge barrier has been built to prevent the penetration of hybrids into the north of America. In this area, Jackson Oz as Dylan Green is working with Tess as a friend trying to get as many people as possible into safe zones. Abraham is working on a drug that would reverse the effects of gas. Aba and Dariel visit Clementine, daughter Mitche. She managed to get her evidence that her father was alive and that she was in the Siberian Stasi Chamber. Jamie is trying to get all the members of the Shepherd Organization responsible for sterilizing humanity and expanding hybrids, which is why he is in conflict with detective Logan.
Jackson and Logan discover a link between the hybrid attacks that occur in Portland and New York; Mitch is interrogated by a woman claiming to be his daughter, Clementine; and a new development in Abraham’s research into the sterility crisis endangers his family.
Abraham and Dariela consider making a deal with Reiden Global for personal reasons, and Jamie and Clementine perform a risky surgery on Mitch.
Abraham and Dariela reunite with the team as they try and stop the hybrids from taking over New York City.
While Jamie’s under arrest, she manages to manipulate Mitch and Logan into helping her hunt shepherds, members of a secretive group responsible for sterilizing humans.
Mitch seeks to rescue Clementine from her captors, and a glimpse into Jackson’s sister Abigail’s past reveals the origins of the hybrids.
The team sets out on a rescue mission for Abe and Dariela’s son, Isaac. Then, in search of information on a new hybrid, Mitch and Jamie travel to California, where they cross paths with a familiar face from their past
Abigail holds Jackson prisoner in order to extract information from him that is critical to her secret master plan, and the team faces a mid-air crisis when their plane experiences an electrical malfunction.
After Mitch’s alter ego, Mr. Duncan, attacks the team’s plane then flees, Jamie, Abe and Max set out to find him and help.
After Jackson attacks Abigail, the team rushes to save her as her life hangs in the balance.
As the team is trapped inside the plane by toxic spores surrounding them, complications arise during the delivery of Clementine’s baby.
After the team’s plane suffers a catastrophic accident in the hybrid zone, Dariela and Tessa set out on a rescue mission to save them.
Season Finale. The team races to stop the hybrids from breaching the barrier wall by shutting down the last beacon that draws them in.
