Small-town reverend Ezekiel Brown enlists outlaw Benny the Teen to lead his people west along the Oregon Trail. Repressed prairie wife Prudence Aberdeen responds to the freedom of the trail, pulling her away from her wealthy husband Todd.
The wagon train must ford a dangerous river, leading to a moral struggle between Ezekiel and Benny over the soul of the group. Meanwhile, Prudence and Todd meet hipster pioneers living #wagonlife.
The wagon train stops in the sinful town of Branchwater, luring Ezekiel into a night of debauchery and temptation. Meanwhile, Benny finds his favorite saloon has transformed into an inauthentic tourist trap.
The wagon train stops at Independence Rock to celebrate the Fourth of July. While Ezekiel and Prudence try to enjoy the holiday, Benny attempts to reclaim his place as the number one outlaw in the west.
The wagon train attempts to cross the Blue Mountains, but Ezekiel worries their journey has been cursed by God. Meanwhile, Benny tries to make amends with Trig.
Sid and Freya find out Freya is pregnant, and Morris throws them a baby shower. Tai has to pet-sit Scraps while going back in time to terminate the future leader of the human resistance.