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Yes

Alyson Stoner as Isabella
Jerry O'Connell as Superman / Clark Kent / Kal-El (voice)
Mamoru Miyano as Kento Miura
America Young as Howleen Wolf (voice)
David Krumholtz as Kareem Abdul Lavash
Vivienne Medrano as Keenie
Scott Innes as Scooby-Doo / Cyber-Scooby-Doo / Shaggy / Cyber-Shaggy (voice)
Yvonne Strahovski as Batwoman (voice)
Rose Byrne as Jexi (voice)
Bryce Papenbrook as Cat Noir
Sally Amaki as Zero
James Monroe Iglehart as Asmodeus
Ellen McLain as Gipsy Avenger A. I. (voice)
Asami Seto as Azest Kingscrown
Sandra Bernhard as Cassandra
Bill Hader as Alpha 5 (voice)
Meg Donnelly as Supergirl / Harbinger
Elisha Williams as Lucas Sinclair
Eric Schwartz as Chazwick Thurman
Rikiya Koyama as Eldemade Dityjon
Emily Osment as Courtney
Marieve Herington as Tilly Green
Hitomi Oowada as Katie Aalto
Takayuki Sugou as Mikado

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