While out for an afternoon drive, Joe Jitsu receives an urgent call from Dick Tracy. Stooge Villa and Mumbles have stolen a racecar- the Spumoni Special- from the city's racetrack. The pair plans to hold the car for ransom. Trailing the two fiends, Joe chases Stooge and Mumbles until he corners them and turns them over to Tracy.
The Brow and Oodles steal Dr. Von Schnooker's notebook so that they can use the mad scientist's invisibility formula. Joe Jitsu follows the twosome and, after drinking the formula himself, the invisible cop manipulates the crooks into drinking a diluted version of the solution. Suddenly, the crooks are only half-invisible, and are easily caught by Dick Tracy.
Stooge Villa and Mumbles are trying to invent a new super gas that will render their victims completely helpless. With such a gas, the pair can commit their crimes without any interference from Dick Tracy and his police detective squad. Tracy sends Hemlock Holmes and the Retouchables to stop the two thugs. Stooge and Mumbles decide that it's time to test their new super gas on the cops. They fire their tear gas, only to find out that the formula for super tear gas is nothing more than a recipe for onion soup. Hemlock and his men capture the pair and turn them over to Dick Tracy.
B.B. Eyes is stealing all of the city's trading stamps. Then he extorts a fortune from the trading stamp center to get their stamps back. Hemlock Holmes and the Retouchables trail the villain to a trading stamp center, where they manage to capture and seal B.B. Eyes' fate by covering the villain's eyes with an entire pad of trading stamps.
Sketch Paree and The Mole have stolen a prize elephant from a well-to-do sultan. Dick Tracy assigns Joe Jitsu to find the elephant and capture the crooks. He finds the elephant hidden inside one of the city's best hotels. After rousting Sketch Paree and The Mole, Joe Jitsu contacts Dick Tracy and turns the two crooks over to his superior.
Having trouble in getting his stolen gold brick back to his new hideout, Flattop decides to work out at the local gym. Unfortunately for Flattop, Joe Jitsu is also working out at the gym. Jo tricks the villain into going into the steam room with his gold brick. Before long, Flattop is turned into a gold statue.
Sketch Paree and The Mole have taken over an Air Force Rocket for the purpose of creating a crime syndicate on the moon. Dick Tracy assigns Hemlock Holmes And The Retouchable Squad to stop them. Hemlock and his men give chase in another rocket. They foil the pair and turn them over to the Moon's authorities.
Disguised as two elevator repairmen, Stooge Villa and Mumbles attempt to break into the Fleabag Hotel's vault. The hotel is missing its elevator. Getting a report of strange activities, Dick Tracy sends Go Go Gomez to investigate. But Stooge and Mumbles grab the detective and force him to help them break into the hotel's safe. Making a radio call to his superior, Go Go asks Tracy to send a patrol wagon outside the hotel. In short order, Stooge and Mumbles are caught again.
Dick Tracy and Hemlock Holmes find out that Stooge Villa and Mumbles have kidnapped the Retouchables. The two villains phone Tracy and Hemlock, and warn them that if the city officials don't capitulate to their demands within 24 hours, the Retouchables will be killed. The two detectives head for Stooge and Mumbles' hideout, where they rout the pair and free their colleagues.
Sketch Paree and The Mole are hypnotizing well-to-do customers at the amusement park, and then taking all their money. Dick Tracy sends Go Go Gomez to the park, disguised as a multimillionaire, to foil the two crooks. Sketch finally corners his prey and begins to put Gomez under his evil influence. Tracy comes on the scene and places a mirror in front of the villain's eyes. Soon, Sketch Paree is under his own trance, and is completely unconscious.
Dick Tracy sends Go Go Gomez to Scotland to stop The Brow and Oodles from ripping off the local citizens by showing off a fake Loch Ness Monster (which is simply a hideous-looking rubber inflatable toy). Unable to get rid of Go Go, the two crooks try to deflate their rubber toy and make off with their booty. But Oodles inadvertently sticks a pin into the hide of the real Loch Ness Monster, and the creature sends the two villains right into the hands of Dick Tracy, Go Go Gomez and the Scottish authorities.
Sketch Paree and the Mole have taken over a Mississippi showboat and turned it into an illegal gambling vessel. Dick Tracy sends Go Go Gomez to stop the two thugs. With the help of a custom slot machine (replete with machine gun firing lever), Go Go apprehends the pair and turns them over to the authorities.
B.B. Eyes and Flattop kidnap the Great Whodunit, a famous magician and escape artist. The pair are forcing the entertainer to teach them his escape secrets so that they can commit crimes without any interference from Dick Tracy and his squad. Tracy sends Go Go Gomez to avert this catastrophe. He does so by tricking the crooks into placing their fingers into Chinese finger cuffs.
Flattop and B.B. Eyes have escaped from prison. In order to make their getaway easier, the two crooks kidnap Dick Tracy and they taken him on flight 22; they plan to drop him into the sea. Tracy contacts Go Go Gomez on his wrist radio using Morse code. Go Go has the airport's radio operator intercept the code and the airlines pilots help save Tracy from the duo.
The Brow and Oodles have stolen Dr. Von Schnooker's supply of shrinking pills. The pair plots to have Oodles (now shrunk to the size of a mouse) break into Spiffany's Jewelry Store and steal all of the store's gems. With the aid of a cat, a diminutive Joe Jitsu foils the fiends and turns them over to Dick Tracy.
Sketch Paree is using hypnosis to manipulate innocent victims into committing crimes. Hemlock Holmes is sent to the theater, where Sketch is posing as a stage entertainer, to stop him. But the crafty fellow uses his powers to hypnotize the cop into stealing cash from the First National Bank. Tracy realizes that his assistant is in trouble. He heads for the theater, where he saves Hemlock and captures Sketch Paree.
Stooge Villa and Mumbles have fixed the big rooster fight between Killer Cock and Skinny Kitty. The villains feed knock-out pills to the champ so he'll fall asleep and loose to the challenger. Dick Tracy sends Go Go Gomez to stop them. Go Go foils the pair by feeding knock out pills to Stooge Villa and Mumbles.
Sketch Paree and The Mole have stolen a secret weapons- a collection of super bombs disguised as apples- and are hiding in the sewers of Paris. The crooks give Joe Jitsu one of the bombs, which creates a massive explosion that causes a flood that sends the trio into the river and into the hands of Dick Tracy and the authorities.
Pruneface and Itchy are using an old castle on a South Sea isle to create and utilize a dangerous collection of atomic explosives for world conquest. Dick Tracy and Go Go Gomez head for the isle. There Go Go, clad in medieval amour, foils the two fiends and turns them over to Tracy and the local authorities.
Pruneface has created a robot that he plans to use to kidnap Dick Tracy. Once in his control, Pruneface will extract the law enforcer's crime-fighting secrets via a brain transfer device. Seeing that his commander is in trouble, Go Go Gomez quickly places the headpiece of the device on the villain's head.
The Brow and Oodles are robbing the city's lumberyard. Dick Tracy sends Hemlock Holmes to prevent the theft, but the fiends capture the cop. They tie him to a buzz saw. Realizing that a member of his squad is in trouble, Tracy heads out to the yard and saves Hemlock by turning off the machine with a trick shot. The Brow and Oodles are captured in a logjam.
Go Go Gomez returns to the United States on a ship with a rare, diamond-studded alarm clock. B.B. Eyes and Flattop try to steal the expensive timepiece. After a chase all over the deck, the two crooks try to throw the clock overboard to prevent capture by Dick Tracy. Luckily, Go Go grabs the clock just as it's about to be thrown into the drink and helps Tracy take the pair into custody.
Someone is trying to scare a retired lawman out of his estate and steal his silver. Dick Tracy and Hemlock Holmes head out West to find out who is behind the events. It turns out that Stooge Villa and Mumbles are frightening the old man with film and recorded images of ghosts, witches, cannons and other things. But Tracy breaks into the house and exposes the scam. As the two cops take the villains away, the former cop reveals that he is The Lone Stranger, and that his "Silver" is actually his horse.
Pruneface and Itchy are stealing from a fountain at St. Peter's in Rome. Dick Tracy sends Charlie out to bring them in. The two criminals attack Charlie from the fountain. Dick assigns Joe Jitsu to help the Italian police chief foil the two villains' scheme. It turns out that the Italian police chief's pet electric eel is the biggest help in sending the two villains to jail.
Two crooks are stealing from patrons on the streets. Dick Tracy sends Hemlock Holmes to stop the crime. The ones behind the thefts turn out to be Sketch Paree and the Mole. The pair are picking pockets in the guise of an organ grinder and his monkey. Hemlock thwarts them and turns them over to Tracy.
Stooge Villa and Mumbles are working from the porch of a high-rise. Operating as "The Pigeon," they use a carrier pigeon with threatening notes to extort money from well-to-do pet shop owners. The message to one: "Return four hundred with pigeon or we will spike your penguin food." Dick Tracy assigns Joe Jitsu to capture the two crooks.
Disguised as an old woman, the Brow is preying on wealthy millionaires by pretending to be their long-lost mother and then killing them for their fortunes. Tracy creates a ploy to have Go Go Gomez impersonate a millionaire. Gomez advertises that he is trying to locate his missing parent. Buying into the sting, the Brow and Oodles invite the two detectives to their lair. There, Go Go and Tracy wrap up The Old Mummy Case in a snap.
Dick Tracy sends Go Go Gomez to the tropics to investigate a real estate scam. Once on scene, the little police detective finds out that Pruneface and Itchy are selling phony islands to unsuspecting victims. Go Go foils the crooks plot by puncturing the inflatable island and turning the pair over to the local authorities.
Stooge Villa and Mumbles have stolen a rare parrot worth millions of dollars. Dick Tracy assigns Hemlock Holmes and the Retouchables to return the parrot and capture the two crooks. Hemlock foils the villains by disguising himself as the parrot and bringing the thugs into Tracy's dragnet... but in the process, two of the members of the Retouchables have captured the disguised Hemlock and hold him for the wagon!
Not having enough evidence that Stooge Villa and Mumbles have stolen Whistler's mother's rocking chair, Dick Tracy has Hemlock Holmes bring the two in for interrogation. Believing that they can beat the rap, the pair agree to a lie detector test. But Dick Tracy's lie detector soon bests Stooge and Mumbles.
Stooge Villa and Mumbles steal one-man helicopters from an air force base. Their plan: to steal from the wealthy residents of The Smetherly Wilshire Hotel. Joe Jitsu foils the two crooks by using mental telepathy to brainwash the pair into thinking that they're double crossing each other, destroy their copters' mechanisms and jump off the rooftop of the hotel and into the arms of Dick Tracy.
Stooge Villa and Mumbles are smuggling rare pearls and hiding them inside Chinese fortune cookies at an abandoned restaurant in Chinatown. Dick Tracy send Hemlock Holmes to find them. Hemlock stops at the restaurant for food and he becomes suspicious of the waiter. Stooge and Mumbles (the waiter in disguise) are about to carve up Hemlock with a meat cleaver. Tracy comes in and foils the villains by shooting a hole in one of the barrels of fortune cookies... which buries the crooks.