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Yes

Will Ferrell as Megamind (voice)
John Rhys-Davies as Gimli / Treebeard
Lake Bell as Patrol Witch / Wagon Witch #2 (voice)
David Kaye as Newsreel Announcer (voice)
Ed O'Neill as Mr. Litwak
Larry King as Doris (voice)
Jon Hamm as Brogan (voice)
Seann William Scott as Crash (voice)
Ernie Sabella as Pumbaa (voice)
Ana Ofelia Murguía as Mamá Coco
Kathy Najimy as Mary (voice)
James Coburn as Waternoose
David Spade as Kuzco / Kuzco Llama
Mike Myers as Shrek (voice)
Russell Brand as Dr. Nefario (voice)
Kevin McDonald as Pleakley
Brad Garrett as Bloat
Rachel House as Gramma Tala (voice)
Eddie Murphy as Mushu
Carolyn Lawrence as Sandy Cheeks
Sterling K. Brown as Lieutenant Mattias (voice)
Christopher Knights as Blind Mice (voice)
Tara Strong as Miss Minutes
Craig Robinson as Cookie (voice)

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