In Berlin, Frank is assigned to transport Delia Weigert (Rachel Skarsten), a rich young socialite to a safe house. Her father, a former influential general in the army (Barry Flatman), has sold off some of his insider military knowledge and Delia is now in grave danger with a German crime lord threatening to kidnap her. With the enemy closing in, Frank must get Delia on a flight back to America, but a sudden betrayal places Delia in deadly jeopardy, and Frank must use all his skills to save her.
Frank races towards Paris to deliver a new eco-friendly motor prototype on time to the Paris Motor Show. But a dangerous hitman, nicknamed "The Wolf", has been hired by an oil company to eliminate him before he can complete his mission. Unfortunately, the protoype emits a signal, enabling The Wolf to track Frank...
While transporting a package, Frank notices the police is on his trail. Ignoring his rules, he opens the package and finds a stolen heart in a cooler, meant for transplantation in a hospital. Frank faces a dilemma when he figures out that his client, Sujic Drago (Mike Dopud), one of the most powerful crime lords in southern France, stole the heart to save his own son, who suffers from a congenital heart defect, and when Inspector Tarconi informs him that another dying boy is waiting at the hospital for the heart. Should he honor his commitment and deliver the package or return it to its initial beneficiary?
On a mission in Philadelphia, Frank finds out his package is Jack Perkins, his old C.I.A. instructor. The blind man is trying to prove his innocence, while an agency mole is attempting to frame him for leaking confidential information and getting fellow agents unmasked. To save his and his client's lives, Frank has only one solution: find a USB key containing evidence that can clear Jack's name and reveal the real mole's identity...
Frank must transport a million euros from Paris to Marseille while racing against two other elite runners each with the same package and destination. The client whose transporter wins will gain an important missile contract. Word of the race has reached two gangs that decide to try and rob the money but Frank, who needs to prove he's the one and only worthwhile transporter on the market, doesn't intend to let himself be swindled... The task is further complicated by a mysterious hitchhiker, who can not be shaken off and wants to know everything about Frank. Frank manages to end up as the lone transporter to finish the race, but victory is bittersweet, due to the loss of an old friend, who was one of the other two transporters in contention.
Frank is to pick up a valuable painting from a gallery and bring it to a rich art collector. There is a wild chase during the transfer and a young woman threatens him with a gun and claims that the painting is hers. Fortunately, at this moment the police appears and Frank seizes the opportunity to wriggle out of the situation. But when he delivers the painting to art collector Max Khyber (Hannes Jaenicke), it turns out that it is a fake. Khyber feels betrayed and suspects Frank. He holds Frank prisoner on his property and sends in a dominatrix to get him to to talk, but Frank manages to free himself and goes in search of the original.
As he's waiting for his package to be delivered in a Toronto parking lot, Frank finds himself faced with a series of strange coincidences. He understands he fell into a trap when the police throws him in jail, accusing him of a crime he didn't commit. His imprisonment is supposed to allow to get a very protected package out of the prison walls: the hand of a mob boss who's just been murdered...
Frank's latest job goes completely wrong: he loses the package and is accused by his employers to have embezzled the money. To prove his innocence, Frank embarks on a search for the real culprits and the trail leads him to old friends from his SAS unit. The soldiers were attempting to settle a score from the past, by enriching themselves and using him as a scapegoat in the process. But when both they and Frank find themselves in danger, they fight side by side - just like old times.