In Brazil, a man has an upside-down head. A girl's face tumour threatens her life.Triplets undergo a second round of life-or-death surgeries. An Argentinian man lives with misshapen tumours and giant-sized limbs. An Englishman can't gain weight.
An American woman has over 50 orgasms a day. A young, soccer prodigy from Brazil who was born without feet tackles a new sport. In the US, a flirty 21-year-old man is only 3ft tall. And a Chinese man has to literally carry his face around.
In Nepal, four sisters suffer from a mysterious condition that has left them unable to move. Meanwhile, conjoined twins find love. A man's chin won't stop growing. A Brazilian girl can't smile. And a Chinese girl with furry patches seeks treatment.
Twin sisters hope doctors can perform a radical surgery to separate them. A Spanish woman covered in blisters. A thai woman has the biggest hand in the world.
In Nepal, four sisters suffer from a mysterious condition that has left them unable to move. A man's chin won't stop growing. A Chinese girl born with hair all over her body seeks treatment. A Brazilian girl can't smile, and conjoined twins find love.
A baby is born with a tumor that takes the form of an extra head. An American man gets a new face.
No arms? No legs? No problem! An American woman's hair won't stop growing and an Italian man covered from head to toe in tumours asks the Pope for a blessing.
A rare infection gives a man a leg the size of an elephant. The world's tallest man can't stand up. Another man goes into shock at any sudden noises. Werewolf boy lives in Brazil.
A strange tumour is taking over a woman's body. A girl gets a completely new face. A Chinese woman copes surprisingly well even though her hands and feet are backwards.
A 16 inch Nepalese elder lobbies to get the record for world's smallest man. They're proud to be the world's tallest married couple, but what about their kids?
A Nepalese man is born with three legs. In the USA, a woman is covered in bubble shaped growths. A woman embraces her facial hair. A Brazilian model is possibly the world's tallest teenager at 6ft 8in. In Indonesia, conjoined twins undergo risky surgery.
A man undergoes risky surgery to stop his body from shaking uncontrollably; a woman's one hundred pound growth is threatening her life and the six-year-old that may become the tallest man who ever lived.
A young boy with a giant neck tumor seeks a medical miracle, a woman and her son both born without arms share an incredible bond and a mysterious skin condition has forced an entire village to avoid the sun.
Weighing over forty pounds at just seven months old, one of the world's heaviest babies needs urgent medical help. A young girl born with her face split in two receives a groundbreaking skull implant and a woman whose legs won't stop growing.
Meet four sets of conjoined twins including five-year-olds headed for risky separation surgery, 12-year-old boys joined at the waist who have found incredible ways to defy the odds and sisters who have been joined at the waist for more than forty years.
A boy whose skin is peeling off holds onto hope, a baby born with a head three times the normal size undergoes surgery and a woman who cries painful crystal tears searches for a diagnosis.
Doctors attempt a groundbreaking full face transplant to save a woman whose face is covered with tumors, a young man's scrotum is growing larger by the day and a pioneering laser treatment provides hope for a young girl who was born covered in hair.
A teenager standing nearly 8ft tall and weighing 400 pounds can't afford to keep growing. A boy born with a tail just wants to fit in. A woman defies the risks of her rare skin disease to have a baby.
A teenager with a face that's rapidly aging searches for a diagnosis, a baby born with an extra head undergoes a risky operation, and a man doesn't allow his fragile condition to hamper his marriage.
A teenager in desperate need of surgery to remove a face tumor, a woman whose body is turning to stone, and a man that has found the perfect use for his enormous arm.
A woman with an extremely rare skin disorder looks more than twice her age. A baby undergoes risky surgery to cure a mysterious brain condition. Three brothers with the same genetic disorder hope for a miracle.
Can doctors save a man with a tumor twice the size of his head? The world's tallest teenage girl hopes a new scientific breakthrough could help her condition. A man with a leg that weighs more than 200 pounds seeks a diagnosis.
A boy with an extra arm growing out of his back considers surgery, a woman whose knees bend backwards faces a series of complex operations and a tumor in a woman's eye could soon threaten her life.
A man with branch like growths covering his hands and feet seeks treatment. A woman's muscles are slowly turning to bone. Two brothers with tumors covering their bodies undergo surgery.
A teenage girl sleeps for weeks at a time, a boy with a brain-crushing skull defies the odds and a unique couple faces a big challenge.
A teenager whose body is aging ten times faster than normal, a girl with a massive tumor in the middle of her face needs emergency care and a woman battling a rare disorder can't stop eating.
An eight year old with a rare form of dwarfism visits a specialist for answers, a young boy with a large mass on his skull needs life-saving surgery, a man believed to be the only person in the world to suffer from a condition called bone dysplasia.
A man born with an extra set of legs finds out whether they can be surgically removed, doctors attempt to recreate a jaw for a young boy who was mauled by a hyena and a woman living with not one, but two rare conditions.
Three young siblings can't stop eating, a man with a life-threatening face tumor must conquer his fear of surgery, a ground breaking operation to separate conjoined twins and two women born with different disabilities excel in sports and life.
An eleven year old boy is 6 feet 9 inches tall and still growing, a man born with no limbs inspires others, technology provides new opportunities for brothers born without toes and a teenager born with a severe skull deformity continues to defy the odds
A teenager with a debilitating skin condition is desperate for relief, a woman struggles to cope with a tumor spreading across her head and a five year old with a rare condition defies the odds
A woman who cries blood is desperate for a diagnosis; an 8-year-old weighs more than 200 pounds; a boy with a painful skin condition needs urgent treatment; a young girl's face is covered in hair.
A man undergoes risky surgery to have a large facial tumor removed; a woman with a rare skin condition defies the odds; a toddler who smokes faces dramatic health consequences; doctors wonder if 7-year-old conjoined twins can be separated.
A boy with a neck growth seeks treatment; a baby born with eight limbs undergoes surgery; a woman shares an inspirational message about her rare condition.
A man has bubble-like growths covering every inch of his body; a rare condition turns a teen girl into a giant; a teen becomes the world's smallest woman; a girl suffers from "Sleeping Beauty" syndrome.
Triplets born with a rare condition need surgery or their brains could be crushed; a boy has legs that have become so large he is unable to move; a soccer star was born without feet; a mother faces criticism after giving birth.
A man with tree-like growths on his hands and feet seeks treatment; a teen who has been hiding a rare condition undergoes surgery; doctors try to figure out why a girl was born with dark hair covering her entire body.
A man seeks to repair his face after being mauled by a tiger; an 11-year-old undergoes fire treatment to lose weight; a boy living with tissue paper skin; a man with a hole in his face search for cures; a model embraces her hairy birthmarks.
A woman who slept through the birth of her child, hopes to find a diagnosis for her sleeping condition; a man with giant genitals seeks help; a 2.5ft teenager hopes to find out what stalled his growth.
A man is slowly choking to death because of his overgrown face; a boy is born with three arms; family members embrace being born with six fingers on each hand; an obese man strives to lose enough weight to have life-saving surgery.
A girl lives with ants in her head; a man undergoes surgery to remove his 132-lb tumor; a woman with a large facial tumor contemplates a life-changing surgery.
A girl's rare disorder causes her eyes to fall out of her head; a man who grows branches from his hands and feet hopes to return home; a baby with a large face tumor.
A boy can't stop his giant foot from growing; a woman with bubbly skin and her kids embrace their condition; a dwarf boy who defied the odds has one more challenge to face; a man with a facial tumor must conquer his fear of surgery.
A woman's leg swells to four times the size of her other leg. A boy living in pain due to his tightened muscles. Can doctors separate a baby boy from his parasitic twin? Two brothers avoid the sunlight.
A boy born with no eyes. A separated conjoined twin adjusts to life after losing his twin brother. Two brothers suffer from a very rare bone condition. A boy living with a huge facial growth finally gets a diagnosis.
The world's tiniest brothers find out if they'll ever be able to grow. Conjoined twins seek separation surgery. A boy with rare brain tumor. A girl living with a face tumor embraces her condition.
The world's tallest child can't stop growing. A man learns to use a dead man's hand. A teenager discovers he has a parasitic twin and it's been growing inside him. A limbless girl gets fitted for prosthetic limbs.
Three year old Anna suffers from a brain crushing prematurely fused skull. Kei was born with no ears but has become a talents musician.
Rebecca vomits up to 12 times an hour and is often hospitalised. Jacque has a lymphatic malformation in her face that means she has never talked.
A boy with undeveloped legs walks on all fours.
Irish twins' muscles and flesh turn to bone.
A man's body blows up like a balloon after a diving accident.
In Thailand, a woman has the world's largest hands. An Ethiopian girl has a life-threatening neck tumor. 4-year-old conjoined twins risk surgery. A young woman has a body affected by vitiligo. And in Spain, a woman's face is blistering away.
A man has surgery on a huge tumor, and a women with a giant leg finds love.
A man with a crippling skin condition live life on his own terms.
A women hopes a tooth transplant in her eye will stop her from going blind.
A women's face is slowing being destroyed by a tumor.
Doctors attempt to separate a pair of conjoined twins at the head.
Conjoined twins Erika and Eva Sandoval undergo a 17-hour surgery. Wells Middleton battles through his new future after losing both his hands.
15-year-old John suffers from epidermolysis bullosa and has no indication of how long he might live. Justice suffers from a rare sleep condition.
After 22 surgeries and losing his right eye, Amit refuses to let his incurable neurofibromatosis define him. Mari Jade suffers from daily fits.
Brandon's life changed forever when surgeons removed a large piece of his skull. Harper's rare condition means she makes skin 10 times faster.
Ravi receives life-changing surgery to remove the huge tumours that cover his face. Lauren has 24-hour treatment to prolong her life.
Natalie suffered major, life-changing burns after a bonfire explosion. Now, aged 18, she's not letting her burns hold her back.
Natalia was born with a rare condition referred to as the 'vanishing bone disease'. Sanja has a condition that causes blisters to form on her skin.
After having her leg amputated, Jillian has surgery which will allow her to use her ankle as her knee. Ashley's condition turns her muscles into bone.
The family of conjoined twins, Callie and Carter, must decide whether to separate them. Abandoned by her birth mother and born with no arms, Deborah refuses to let her tragic early life hold her back. Josh shares his life as 'The Tourette's Barber'.
Both born with brittle bone disease, Dejua and Antwon have suffered over 600 breaks between them. Robert's spine is not connected to his hips.