Tim’s Dad sends Eric a gift basket wishing him luck on the new show. Leif and C Boy square off in a hackey sack championship. Dr. Steve Brule does a report on fruits and vegetables. Casey and his Brother perform "Time Travel" on The Uncle Muscles Hour. Tim and Eric revive the Old Waiting Room Sketch. The new Cinco toy, "B'owl", is advertised. And Tim makes a call to pest control about his bees and his disappointing son, Spraynard Krugar.
Cinco Insurance advertises their "Balls Insurance" plan. Eric sends Tim an ornamental hot dog after finding out he is dying of "Limp Lip." Dr. Steve Brule celebrates 10 years in broadcasting. Eric looks for his Chippy. Pierre teaches children how to dance and scolds them for allegedly possessing rotten meat. Tim and Eric try to write a jingle for Rolos.
Tim learns a new magic trick that runs him into some problems. “Kid Break” shows children that it’s okay to sit down while you pee. Tairy Greene teaches new Gravy Robber employees the best gravy robbing techniques. Tim draws free portraits on Hollywood Blvd. And Jaime Stevens returns home from his summer abroad with newfound powers in “Kitty Cat Man”.
Steve and Mike Mahanahan advertise their child clowns and child clown shoes. David Liebe Hart and his puppet Jason sing about the Korendians and meeting in the light. Tim and Eric give a seminar on how to build a successful sitcom writing career. And Tim and Eric's assistant, Simon, presents them various numbered elderly ladies in "Here She Comes."
A keytar group plays a song about sports. Carol's secret love for her mean boss finally reaches a boiling point. The new Cinco toy, "T'ird", is advertised. Danny Mothers interviews Glen Tennis about his second film "Crystal Shyps". Vernon does some ventriloquism with his potty mouthed dummy, Horsy, with Richard Dunn on the drums. And Eric pulls a prank on Tim.
Success. Tim and Eric’s replacements host the show. The Beaver Boys go clubbing, try to pick up some ladies, and enjoy some good shrimp and white wine. David Liebe Hart returns with a new puppet and a new song about staying in school. Tragg shows his viewers how to make some of his famous slop on his cooking show “Tragg’s Trough”. “Kid Break” returns with a rap about wearing your dad’s dirty socks. And surplus media distributor Ken Tulley advertises his series of “Fitness Can Be E-Z” tapes and throws in some great deals along with them.
We get a glimpse of Pall Willeaux’s dreams as he advertises his “Lazy Horse” mattresses. Tim & Eric replace their crew with elderly men. Tim and Eric beatbox. David Cross sings a song about abstinence to Abbey Brooks in the porno film “Pizza Boy”. The Channel 5 Married News Team gives live coverage of the “No Sex Hot Dog Parade” as part of “No Sex Week”. Maria Bamford talks about skin care and her abusive mother on her show “The New You”. And Eric has some trouble with the computers at the “Cinco Personal Banking Center”.
Tim and Eric are late in delivering the episode to the Network and must rely on Hamburger Taxi to get the tape there on time. Dr. Steve Brule helps out the Married News Team with a special report on stomach and digestion problems. Tim makes a call to a music store about his uke’ that keeps falling on his computer. Two men get in a fight over a car crash and settle it with a dance-off using their pygmy Tim and Eric dancers. A kid searches for his Chippy in a claw vending machine. And Michael Q. Schmidt performs his new "Raise My Roof" dance to win the "Uncle Muscles Grand Championship" dance-off.
“Tim and Eric Awesome Show, Great Job!” celebrates its 50th anniversary hosted by Pat Dudley, but Tim and Eric haven't spoken to each other since an unfortunate stairway incident. Pierre teaches children how to meditate and asks for their dads' email address. Bob Odenkirk advertises "E-Z Kreme", an all-natural diarrhea inducer. Richard Dunn plays an improv game with himself on the show “Dunn-Prov”. And Cinco advertises their handy “MIDI Organizer Filing System”.
The Uncle Muscles Hour is disrupted when Casey wanders off and Casey’s brother is forced to adapt to life without him. Dr. Steve Brule teaches us about modern fashion, resulting in some tension between Jan and Wayne Skylar. Eric talks about his collection of Rascals on "Nights with Tim Heidecker". And the new Cinco product, "B'ougar", turns your imaginary fears into real ones.
The fate of Casey is revealed. Eric returns from vacation with a video created by his new best friend detailing their exploits. B.M. Fahrtz advertises the "Poop Tube". Raz's presence on the Tim and Eric set instigates awkward jealousy. Magician Gregory hosts "Trick My Trick". Uncle Muscles introduces a clip from the Casey vault, "Hamburgers and Hotdogs". Celebrity impressions by James Quall. Tim's new best friend, plus video!
When Tim and Eric run out of show ideas, Aboxa balloons drops by. Steve Brule has a report about the internet, where he then makes a video, and hopes it will go viral. C.O.R.B.S (Cops on Recumbent Bikes) attempt to stop a group of Colombian terrorists trying to take over a sugar factory, which ends in a terrible tragedy, and some sound effects. Grill Vogel teaches you how to hug appropriately in a workplace. We're also introduced to a family dealing with divorce, and the Cinco Eye Tanning System. (John C. Reilly and Ray Wise)
Jim and Derrick board, Chug, and get chill with Elisha Cuthbert in the zone. You just got bonged! And damn... Drez plays it all back. Also, Cinco's Pep Pep makes an appearance. (Elisha Cuthbert and John Mayer)
Tim and Eric lead their jazz band through jazz chatter scats. The Beaver Boys visit a restaurant and come into contact with some shrimp and white wine. How do you truly clean up after your cat? (Maria Bamford and Bill Hader)
Tim and Eric hire Tommy Wiseau to direct a "Pig Man" sketch for them. Features clips from The Room. Cinco introduces the Mancierge service.
Cinco introduces the C-Bund as a "great alternative to pants", Tim graduates from barber school, "Live With my Dad" song, J.J. Pepper's Videography ad(guest starring Will Forte), Afternoon Review, Eric ruins Tim's graduation party, "Reasonable Shirts", Cinco Musical Tapes presents "Groban sings Casey" ad.
Ben Hur hosts The Ben Hur Show Awesome. Includes a commercial for FreeRealEstateForJim.biz, a Kid Break about bloody nipples, Channel 5 Presents The Human Body with Dr. Steve Brule, Tim and Eric both want to be President during a press conference, "White Boys", Michael Ian Black Focus on Comedy with guests Tim and Eric, and an ad for The Best of Pusswhip Banggang album.
Tim writes the semi-autobiographical novel Choices: The Problem with Eric Wareheim, much to Eric's dismay. Meanwhile, the Cinco H'amb saves another life by offering a cheaper alternative to expensive food products (Guest starring William Sanderson). Two actors discuss their achievements in All Dolled Up, and Dr. Steve Brule delivers a depressing message.
The half-hour series finale. Tim and Eric are gearing up for the holidays when they begin to lactate. Thinking quickly, the boys (and Eric's son Koi) decide to bottle their man milk to give as holiday gifts. However, they neglect to pasteurize the milk, killing everyone. Meanwhile, Ben Stiller and Ben Hur join forces to form the dynamic comedy duo Ben StillHur, Cinco unveils its Privacy Helmet, David Liebe Hart sings about overseas STDs, and Paul Rudd watches dancing men on a computer and becomes smitten with Tayne.