Sam Ryan recruits the Lyell team to investigate the assassination of the health secretary, but Nikki is unsure whether Sam knows more than she's letting on.
| Name | Type | Role | |
|---|---|---|---|
| Ed Whitmore | Writer | ||
| Tom Benedict Knight | Guest Star | Dan Clemence | |
| Emma Beattie | Guest Star | Alice Reynolds | |
| Lloyd Everitt | Guest Star | David Mashaba | |
| Stephen Donald | Guest Star | Charles Black | |
| Gaia Wise | Guest Star | Jo Reynolds | |
| David Leon | Guest Star | Oscar Harris | |
| Jacqueline Oceane | Guest Star | Assassin 1 | |
| Hugh Quarshie | Guest Star | Jomo Mashaba | |
| Ian Puleston-Davies | Guest Star | DSI Ronnie Boyle | |
| Will Bowden | Guest Star | Assassin 2 | |
| Díana Bermudez | Guest Star | Rosa Hernandez | |
| Shireen Farkhoy | Guest Star | DS Martine Chalal | |
| Matthew Gravelle | Guest Star | Tom Faulkner | |
| Gina Bramhill | Guest Star | Fiona Mashaba | |
| Bill Anderson | Director |