Quarterfinal play continues in the 2010 National Heads-Up Championship, with $75,000 secured and just two wins separating the players from the $500,000 title. At the feature table, Scotty Nguyen battles Jason Mercier. On the outer table, Erik Seidel takes on Peter Eastgate for a spot in the semifinals.
| Name | Type | Role | |
|---|---|---|---|
| Leeann Tweeden | Host | Herself - Commentator | |
| Oliver 'Ali' Nejad | Host | Himself - Commentator | |
| Craig Hummer | Host | Himself - Commentator |