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Owner of a Lonely Heart

Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr. Addison Shepherd decides to teach Izzie a very painful lesson.

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  • Originally Aired December 4, 2005
  • Runtime 43 minutes
  • Content Rating United States of America TV-14
  • Production Code 207
  • Network ABC (US)
  • On Other Sites IMDB
  • Created May 1, 2021 by
    Waad.88
  • Modified March 17, 2024 by
    PhoenixGrey
Name Type Role
Mark Wilding Writer
Margaret Welsh Guest Star
Sarah Utterback Guest Star
Timothy Bottoms Guest Star
Rosanna Arquette Guest Star
Curtis Armstrong Guest Star
Pat Healy Guest Star
Daniel Minahan Director