シリーズ５作目。「魔法が使えたら便利にちがいない！」と思いついたのび太は、もしもボックスで魔法の世界を作り出す。だが、ここでもやっぱり不器用なのび太は、魔法がうまく使えない。
そんな中、ドラえもんたちは、魔学博士の満月先生と娘の美夜子に出会い、魔物たちが支配する“魔界”が今、地球に接近しつつあることを知り…。
Nobita requests of Doraemon the Moshimo-box and wishes for the world to become a place where the use of magic is possible. Witchcraft replaces science and technology and everyone makes use of it on their daily lives, except for Nobita, who, like usual, isn't very good at conjuring spells. Frustrated, he plans on returning things to their past state, but his mother threw the Moshimo-box away.
