It's November 1967 and nurse Colleen McMurphy faces the last week of her tour of duty in Vietnam, dealing as usual with the dying boys, primitive conditions, and the advances from pilot Natch Austin. USO singers Georgia Lee and Laurette Barber arrive to entertain the troops in the base's new R&R center. Brand new Red Cross volunteer Cherry White also arrives, determined to find her brother, a marine whom her family lost contact with.
Laurette faces an important audition with laryngitis. Beckett battles the pressure of racial prejudice and financial coercion when he discovers someone has been using the body bags in his GRU. Dr. Richard returns from R&R in Hawaii disillusioned by the perceived changes in his wife. Dodger finally finds Rick, Cherry's long-lost brother.
Lila takes over command of China Beach and orders KC off the base. McMurphy finally lets herself admit how much she cares for Natch when she receives some disturbing news about him. Wayloo Marie Holmes, former Saigon weather girl, arrives at China Beach to handle her first journalism assignment, extolling the recreational facilities at the base.
Wayloo Marie tries to keep reporting, McMurphy and KC are trapped in an officer's restroom, Beckett is held prisoner by Mai's brother and Dr. Richard and the wounded Dodger prepare to defend the hospital during the fierce fighting of the 1968 Tet offensive. Cherry comforts another Red Cross volunteer at a firebase.
Wayloo Marie becomes intimidated by the war as its reality sinks in following Cherry's death. McMurphy tries to fight the bureaucracy to keep Dodger from going to Japan for more medical help. KC fights her heroin habit as she tries to locate Cherry's brother and prepares to accompany her body home to Iowa for burial.
Beckett faces going home when his tour ends in April 1968, as the assassination of Martin Luther King, Jr polarizes black-white relations in the nation and at China Beach.
McMurphy uses a little guilt and a little blackmail to get a reluctant K.C. to visit a wounded soldier whose face has been badly disfigured. Holly, the new doughnut dolly, challenges the nurses on behalf of the Red Cross Volunteers to compete in a Miss China Beach beauty pageant. Frankie is assigned to the motor pool and runs into Sarge Pepper, who's not very eager to have her there.
Dr. Richard worries over a craniotomy that has permanently altered a patient's mental capacity; Lila faces an inspection that will determine if she gets a key promotion; Sarge Pepper asks for some advice about courting Lila and K.C. finds herself in a very awkward position when a senior officer goes AWOL on her permanently.
China Beach celebrates a soggy Independence Day with Boonie and Holly trying to keep everyone's spirits up, McMurphy dealing with a love struck private as she tries to sort out her feelings for Dr. Bernard, Lila and the Sarge discussing the future and Beckett and K.C. quarreling over registering the dead to vote.
A pair of ballroom dancers bring a note of grace and harmony to the uneasy relationship between McMurphy and Dr. Richard while completing a mysterious mission of their own.
K.C. finds herself in the middle of a C.I.A. assassination plot, and dependent on McMurphy to vouch for her innocence.
In November 1966, fairly new guys Colleen McMurphy and Dr. Richard find themselves learning the ropes when they arrive at China Beach.
McMurphy finds herself under suspicion when a wounded G.I. she doesn't remember names her as his beneficiary. Lila has mixed feelings about an old friend who now outranks her and has arrived at China Beach to do a recruiting film about Army nurses.
With everyone else away for a distant USO show, K.C. and McMurphy indulge in an alcoholic binge that takes them to a dreamy landscape where a Native American guide tries to help them heal past and present wounds.
In 1985, a reunion between Boonie and Dr. Richard stirs up memories of their first meeting in Vietnam in 1966. It also brings up questions for Boonie's 18-year-old adopted daughter, Karen.
Still in 1985, Karen learns how her natural mother, KC, coped with her pregnancy by turning to Boonie for help.
In Saigon in 1967, KC gives birth with McMurphy's help and gives the baby over to a foster mother.
While attending his father's funeral in 1985, Beckett reflects on his childhood and his tour of duty in Vietnam with the Graves Registration Unit.
In 1970, McMurphy returns home to Lawrence, Kansas to make peace with her mother and try to settle down into civilian life, but finds both goals beyond her grasp.
In 1972, Dr. Richard and his nurse take a romantic trip to Florida, where they run across a hard-livng McMurphy working at an orange-juice factory.
In 1969, China Beach watches from afar as the first men land on the moon. McMurphy simmers jealously as Dr. Richard falls for a new nurse. Beckett entertains a group of USO singers in his G.R.U. hut. A disturbed Boonie meets with a tragic accident.
Suddenly back home and missing one leg, Boonie begins a slow and painful re-entry into civilian life with the comfort of a loving nurse.
Frankie returns to Chicago in 1969 to try her hand at being a standup comic but runs into the tragically funny trial of the infamous Chicago Seven. Back in Vietnam, McMurphy tries to help Dodger convince some Montagnard tribes people to evacuate their homes.
McMurphy meets a sympathetic drummer at a 1983 wedding and recalls the 1969 wedding of Lila and Sarge Pepper, as well as the end of her relationship with Dr. Richard.
The imminent fall of Saigon reunites KC with her daughter as she struggles to get the little girl out of Vietnam and safely to America and a waiting Boonie. In the 1980s, a cynical McMurphy tries to prevent further child abuse in New Mexico.
The arrival in Bangkok in 1969 of a hard-drinking McMurphy and a young private disrupts KC's carefully developed new life and brings back unwanted memories.
In 1976, McMurphy helps KC re-enter the country and find her daughter before heading out to Montana to visit Dodger, who's coping with a disabled father and raising his son Archie alone.
In 1985, Karen begins a videotape project interviewing China Beach veterans about their experiences in Vietnam and their memories of her natural mother.
In 1985, an increasingly angry Colleen torments herself and her husband until she discovers she's suffering from post-traumatic stress syndrome and seeks help to deal with the memories of her final weeks in Vietnam.
Colleen attends a China Beach group reunion planned by Boonie, and recalls her last day in Vietnam. Karen comes to terms with the ghost of her absent mother, K.C.