Dio captures Casshern and brings him back to Luna's castle. Leda wants Dio to be healed along with her by Luna, but he refuses. Leda finds Luna and orders her to heal only those that are chosen, like her. Meanwhile, Braiking Boss is followed by robots on the verge of ruin. Leda receives Luna's healing, but it is not enough as she starts to break down again. She demands more healing from Luna, who complies. However, the increased healing she receives is much more painful than the first one. Dio takes Casshern away for him to regenerate so that he can battle him again in a fair fight. Casshern learns that Dio's reason to live is to defeat him. After a painful regeneration, Casshern prepares for one final battle with his arch-nemesis.
Dio riesce a imprigionare Kyashan nel suo castello. Leda, intanto, cerca di costringere con ogni mezzo Luna a guarire Dio.
ディオの軍団の前にルナの街は占拠された。ルナはレダに隔離され、その癒しは選ばれた者にしか振るわれないこととなった。一方、城の地下にはボディを無惨に砕かれたキャシャーンが横たわっていた。その中、徐々に再生を始める不死身の肉体。その様子を眺めつつディオはキャシャーンを倒し、彼を越える思いを強くする…。