Dr. Oliver Wolf reluctantly accepts a job at Bronx General Hospital where he's forced to work with a team of interns as they treat a mother who can no longer recognize her children.
When a high school girls’ basketball coach faces a debilitating illness, Dr. Wolf must help her reconnect with her body before it’s too late. Ericka and Dana treat a frat boy who sees dragons.
A member of a biker gang seeks out Dr. Wolf's help as he grapples with life-threatening memory loss. The interns are tasked to help a young girl struggling with mysterious seizures.
When a bloody bride stumbles into Bronx General, Wolf races against the clock to save her.
Wolf must help a Marine grapple with mysterious symptoms before the birth of his child.
Dr. Wolf and the interns go back to high school to treat a group of pregnant teenagers.
Dr. Wolf and the team perform their most experimental treatment yet: a brain-computer interface implantation in their John Doe patient's brain.
When an elderly woman is brought in with signs of dementia, Dr. Wolf investigates whether she's suffering from a neurological disorder or having a late-in-life awakening. Dr. Pierce grapples with a chilling discovery about one of her patients.
When an artist refuses to paint for his upcoming show, Dr. Wolf and his team must figure out why. Dr. Pierce goes into uncharted territory with a patient.
An unexpected patient crashes into Bronx General with mysterious life-threatening symptoms.
Dr. Pierce treats a patient in crisis, presenting an ethical dilemma. Dr. Wolf and Dr. Nichols disagree on how to treat a patient.
Dr. Wolf and his team face their biggest challenge yet when an apartment building collapses in the Bronx.
Dr. Wolf meets a pastor dealing with mysterious visions. The interns grapple with the fallout from the building collapse.
As Wolf deals with a personal crisis that brings up dark corners from his past, the interns assist an MMA fighter exhibiting strange symptoms. Meanwhile, Pierce is visited by Bitsy, an Upper West Side housewife with a penchant for gossip, who gives her some shocking intel about a nearby influential surgeon.
A reality show contestant lands at the hospital with an unusual delusion. Dr. Pierce fights for her future at Bronx General. Wolf clashes with Frederick over a personal matter.
Dr. Wolf and his team treat a young patient accused of a serious crime. Dana navigates unfamiliar territory in the romance department. Pierce returns to work.
Dr. Wolf and Dr. Pierce are tasked with a house call to evaluate a woman under a conservatorship. Dr. Kinney's curiosity is piqued by a patient outside the hospital.
Dr. Wolf and Dr. Nichols must do whatever it takes to keep two patients in critical condition alive.
