After Juana loses her entire family in front of her eyes, she manages to make it out alive and assumes a new identity to go into hiding. Meanwhile, elsewhere, the leader of the band "El Cruce" is murdered after he attempted to stop a drug sale, and his brother "Hache" must take his place.
Hache y Juana provienen de mundos totalmente opuestos, pero la noche en que accidentalmente nace la banda Cumbia Ninja, en las entrañas mismas del peligroso barrio La Colina, los destinos de Juana y Hache quedan unidos para siempre.