ZuZu Becky Jones is broadcasting her Brain Vlog when alien SuperNuffs crash land their space tub right into her room! But when Uncle Sirius snatches one of her new friends, ZuZu & the SuperNuffs must team up to rescue him.
SmartNuff invents a Splurkle Buster to get rid of Splurkle super fast and ZuZu & the SuperNuffs head to the factory floor to try it out. But when EdE turns the buster to 'maximum power' the machine overheats and things get out of control.
ZuZu takes a mind ride to PlanetNuff to visit the Nuff's home. But when EdE uses the mind ride crystal as a bowling ball - it breaks in half and the Nuffs and EdE find their minds have been swapped into each other's bodies! To make matters worse, ZuZu's mind is trapped in the Multiverse and without the crystal it can't find it's way home.
When the Nuffs try to help ZuZu with her homework, they accidentally create an out of control volcano which heads straight for the factory! ZuZu & the SuperNuffs must work together and use magic think to stop the volcano, before it's too late.
CuteNuff is furious when ZuZu borrows her kickety-punch boots without asking. But when EdE brings a machine to life that he shouldn't, they find themselves chased through the corridors of the factory by a crazed contraption and ZuZu must borrow CuteNuff's boots one more time to try and make things right.
After CuteNuff beats BuffNuff in an arm wrestle AGAIN, BuffNuff starts to question if he really is the strongest Nuff in the Multiverse. While working out in the Gadget Graveyard - BuffNuff inadvertently causes a landslide and is trapped underneath the rubble. When the Nuffs realise he is missing - they set out to find him but with all that rubble piled up - it seems like they could lose a" Nuff forever.
When SmartNuff spots a wormhole in the Multiverse, the Nuffs decide to see if they can fly back to PlanetNuff. But the unpredictable wormhole takes them 35 years into the past, where they meet the young Uncle Sirius - when he still knows how to have fun!