Los Angeles-based mega-billionaire Diana - who collects planes and a multitude of transforming aircraft called "Ultimates" (no invisible plane in sight here) - as she attempts to take down an evil pharmaceutical company run by morally corrupt scientist Veronica Cale, who is mass-producing a human-growth hormone that is causing its users, mostly black inner city youth, to die. Along the way, she tackles criminals, a Senate subcommittee, and a broken heart, the latter courtesy of lost love Steve Trevor.