The event was headlined by a UFC Lightweight Championship bout between then champion Eddie Alvarez and UFC Featherweight Champion Conor McGregor. This was the second time in UFC history that champions in different divisions fought for the same title. The first time was at UFC 94 on January 31, 2009, when then-welterweight champion Georges St-Pierre defended his title against then-lightweight champion B.J. Penn.
| Name | Type | Role | |
|---|---|---|---|
| Eddie Alvarez | Guest Star | ||
| Conor McGregor | Guest Star |