For thousands of years, the culture and people of Southeast Asia have been shaped by the flow of the Mekong River. However, the Mekong is undergoing incredible changes as a combination of climate change, overfishing and dams on Mekong tributaries have caused fish populations to plummet and altered water quality. The Water Brothers travel up the Mekong to learn how its conditions are changing and how a series of 11 planned mega-dams will further affect the river and its people.