A dog that can detect cancer faster than doctors can do it by using sophisticated equipment; a horse that can read minds; birds that can sense disaster days before it happens.
| Name | Type | Role | |
|---|---|---|---|
| Kevin Burns | Writer | ||
| Rob O'Brien | Writer | ||
| Brian Leff | Writer | ||
| Jeff Stepp | Writer | ||
| Jeff Stepp | Producer | ||
| William Shatner | Host | ||
| David Ramey | Guest Star | Self - Equine Veterinarian | |
| Chris Pachel | Guest Star | Self - Board-Certified Veterinary Behaviorist | |
| Roger Edwards | Guest Star | Self - Edinburgh Resident | |
| Abbie Johnson | Guest Star | Self - US Navy, Petty Officer 3rd Class | |
| Tok Thompson | Guest Star | Self - Assoc. Prof. of Anthropology, USC | |
| Claire Guest | Guest Star | Self - Chief Scientific Officer, Medical Detection Dogs | |
| Paul Waldau | Guest Star | Self - Author, Animal Studies: An Introduction | |
| Loyd Auerbach | Guest Star | Self - Parapsychologist | |
| Charmain Leitch | Guest Star | Self - Edinburgh Resident | |
| Ernie Perez | Guest Star | Self - US Army, M1 Armor Crewman (19K) | |
| Henry Streby | Guest Star | Self - Ecologist, University of Toledo | |
| Dr. Travis Taylor | Guest Star | Self - Astrophysicist | |
| Nicole Land | Guest Star | Self - Prof. of Equine Science, Pierce College | |
| Debra Horwitz | Guest Star | Self - Veterinary Behaviorist | |
| Nan Hauser | Guest Star | Self - President, Center for Cetacean Research and Conservation | |
| Stephanie Herfel | Guest Star | Self - Cancer Survivor | |
| Michael Dennin | Guest Star | Self - Physicist, Univ. of California, Irvine | |
| Rupert Sheldrake | Guest Star | Self - Author, Dogs That Know When Their Owners Are Coming Home | |
| Joan Blank | Guest Star | Self - Founder, Dream Catcher of LA | |
| Briana Abrahms | Guest Star | Self - Research Ecologist | |
| Sierra | Guest Star | Self - Stephanie Herfel's Dog | |
| Kirsten Fisher | Guest Star | Self - Professor, Cal State LA | |
| Tony Broonford | Guest Star | Self - Local Historian, Edinburgh, Scotland | |
| Brett Joseph Page | Guest Star | Self - US Marine Corps, Force Recon Operator | |
| David Whitehead | Guest Star | Self - Investigative Journalist/Radio Host | |
| David M. Kushner | Guest Star | Self - Oncologist | |
| Susan E. Leventhal | Executive Producer | for HISTORY | |
| Rob O'Brien | Executive Producer | ||
| Kim Egan | Executive Producer | ||
| Kevin Burns | Executive Producer | ||
| Anthony Fiorino | Executive Producer | ||
| William Shatner | Executive Producer |