Zack and Cody try to make friends at school. When word gets out that they live at the Tipton, all of the cool kids hang out with them. In the end, the twins find out who there real friends really are. Meanwhile, Carey is practicing dance moves, while London teaches Maddie how to ask Lance out and Maddie tutors London in Math.
A beauty pageant comes to the Tipton Hotel. Cody ends up becoming a contestant, because of a girl he likes to meet. Zack wants him to win, so they could use the prize money for new bikes.
Zack and Cody have two pet rats as a science project. Mr. Moseby gives the twins tickets to a Red Sox's game to get them away from the hotel. Then a hotel inspector seizes control of the Tipton, because of Zack's mistake. London has a dog party for Ivana and Maddie has to plan.
When the twins get grounded for running around in the hotel, they try to take a picture of a $20,000 kiss so that they will no longer be considered burdens.
Zack and Max compete in a dance contest. Cody learns how to do magic. Zack injures himself, and Cody has to take his place in the dance finals. Maddie becomes London's servant after London lends her money.
Maddie has her prom at the Tipton Hotel after realizing there is nowhere else to have it. Zack thinks that he will be her date, but ends up getting dissapointed. Cody starts to act like a mime.
There is a Battle of the Bands competition being held at the Tipton Hotel. Zack and Cody, along with Max and Tapeworm compete against Maddie's band in which has London in the band.
Cody ends up going away to camp. Zack starts to miss him, and has to find a way to get to him. London ends up learning how to drive, with the aid of Mr. Moseby.
There are a couple of jewel thieves in the Tipton Hotel. Zack and Cody have to try and find out who it is to clear up someone's name.
When the twins find out about hidden treasure in the Tipton, everyone goes into a frenzy looking for the money.
London's father goes broke due to an investment in a diamond mine. London now has to move in with Maddie. Zack and Cody wonder if their parents ever got them mixed up when they were babies.
London develops a crush with the son of a rival hotel owner, of which Ilsa is the the manager. Zack and Cody bake cookies to be served at a ball held at the Tipton.
London spreads a rumor she started about Maddie, and Maddie accidentally spreads one about London. Cody wants to look different, because people kept on thinking he was Zack. Cody has Zack fill in for him on an interview, because of a certain problem.
Carey needed some help, so Mr. Moseby ends up taking Zack and Cody to a baseball game. Mr. Moseby get into some trouble due to an incident at the game. London sets Maddie up on a blind date, in which Maddie ends up having a really bad hair day.
Jesse McCartney checks into the Tipton Hotel and Maddie, London, and Zack break into Jesse's room. Zack collects discarded items belonging to Jesse, so he could sell them. Cody enters a science fair, and receives help from Arwin.
After getting bad grades on his report card, Zack decides that he needs a way to get good grades without having to study. When Bob, a boy with Dyslexia, shows up in his class, Zack decides that he can pretend to have dyslexia so he can have more time on both tests and reading. Meanwhile, London beats Maddie at chess, and soon Maddie becomes obsessed at beating London at chess.
When the twins find out about a ghost in Suite 613, Zack will stop at nothing to meet the ghost. With some help from Maddie and London, the twins come face to face with the ghost of Irene.
Kurt, a rock-musician and the twins father, comes to the Tipton Hotel for a visit. Kurt will allow Zack and Cody do things that Carey would not approve of them doing. Zack decides to leave the Tipton when he gets in an argument with his mother about his homework, by stowing himself in his father's tour bus.
Zack, Cody, and the entire gang get snowed in at the Tipton. Maddie riggs a ""secret santa"" bowl so that London will get her a gift.
Max ends up kissing Zack, after winning a basketball game. Maddie helps London with her shopping problem, because of something said by London's father. There is a surprise involving Carey and a certain someone.
Cody is inspired by a guest speaker and tries to do the same with his friends - to hilarious results. Meanwhile London and Maddie compete savagely in the fashion shootout of the year to get on the cover of Teen Trends.
A girl at school likes Cody, but after he hires Zack to help, she falls for Zack instead. London's dog Ivana and Maddie's dog Scamp fall in love.
The Tipton shoots a commercial. The director happens to be a date of Carey's from 15 years ago whom she left in the middle of the date. He prevents Carey from trying out for the commercial—but in the end, Carey and the twins end up being in the commercial.
Maddie helps London become smart to win over the affection of a scholar. Meanwhile, Cody moves into the coat closet and makes it is own room after he has enough of Zack's sloppiness.
Zack and Cody fall for a French girl who can't speak English very well. Meanwhile, somebody steals London's purse and Esteban tries to help.
Maddie runs a Daycare Service at the Tipton, and when Maddie has a family obligation to attend to, Zack and Cody take over. Meanwhile, London encourages Mr. Moseby to take yoga to help him relax a bit more.
A food critic is coming to the Tipton Hotel. Cody ends up having to fulfill the duties of being head chef, after the Tipton's regular chef suddenly quits, on a very important day.
The boys end up trying to save a horse, which is no easy task trying to keep it hidden. Maddie loans something that is very sentimental to her to London and is mad at her when London loses it.
Zack and Cody have to repair a wall that they damaged as punishment. London begins attending Maddie's private Catholic school due to her poor grades.
Cody runs for class president; Zack decides to run as well, but for the wrong reason. Mr. Moseby gets annoyed with one of the staff members.
Mr. Moseby gets worried when his older brother Spencer arrives at the Tipton for a visit. Zack and Cody buy a bike, but they have to share it. Maddie and Esteban mess with London's horoscope.
Cody is disappointed when he finds out that Zack is doing better than him in woodshop at school. London takes credit for a book that Maddie wrote.
Maddie is having her Sweet 16, and likes to have her party at the Tipton. On that same day, London decides to throw her own bash. Zack ends up trying to figure out what to get Maddie for her special day.
A twins convention is being held at the Tipton Hotel. Zack ends up creating a double date with twin sisters, for him and Cody. London and Maddie end up enjoying a evening with twin brothers.
Zack borrows money from a guest named Maynard to play video games, but starts to fear him when he can't pay it back. Cody enters a spelling bee. London and Maddie help a homeless family.
Mr. Moseby and the Tipton Staff is challenged to a bowling competition, by its rival, Ilsa and her team. Zack is the star bowler for the Tipton, but ends up having to be replaced due to getting grounded. Zack's replacement must overcome his emotional scars, due to a past bowling incident.
Zack makes a new rich friend, who is mean to Cody and thinks he is a dork. Maddie and London have to do a parenting project for school as partners.
Zack and Cody discover a machine of Arwin's creation that can transport people from one dimension to another. They hop in, and find themselves back at a mixed-up version of the Tipton Hotel; where London is a candy girl/babysitter, Maddie is an air-headed rich hotel heiress, and other personalities are switched.
Arwin could win a trophy and a kiss from Carey, if he ends up winning an annual competition for "Hotel Engineers"; in which the boys help Arwin train and compete. Maddie ends up getting hired by London to work at her new boutique.
Zack dreams that he has gone back in time to the Boston Tea Party with his family and friends, where an act of protest by Maddie inspires the him to launch a present-day battle to save a historical park in Boston that's being threatened to be demolished.
A hotel guest trips on Zack's skateboard in the lobby. But when the boys find out that's he's lying in order to get free service, they come up with a plan in order to set things straight.
Cody gets Zack a job at the school newspaper for the advice column since the previous person quits. When a girl he likes asks for advice, Zack tells her secretly to ask him out. So she does. But when she finds out about him giving the advice, Zack is in for a load of trouble. London can't sleep and Maddie, Mr. Moseby & Esteban try to help her sleep.
Raven Baxter is stuck in Boston, where she has a vision that something bad will happen to Cody. After warning him, vaguely, he becomes paranoid. Meanwhile, Maddie tries to get London into wearing Raven's dress, but London is too stuck up to do so, until pop star Hannah Montana arrives at the Tipton, and wants to wear the dress herself.
One of Cody's favorite bands is playing a concert at the mall. Cody is tempted to skip school with Zack and Bob, so he can see the band perform. Meanwhile, London meets her new young step-mother.
Zack and Cody's school is putting on the Shakespearean play, "A Midsummer Nights Dream", where Cody tries to keep a certain kiss involving his new girlfriend and Zack from happening, and Zack tries to get a girl. London uses the principles of feng shui as she redecorates the Tipton.
Cody, is having difficulty dealing with the fact that Carey has a new boyfriend. But, Zack and Kurt do not have a problem with him because he is rich. London joins Maddie's volleyball team and ends up being rather good- but only when she is mad.
Zack convinces Cody, Jessica, and Janice to go see a scary movie, but when it's Zack who gets scared, Cody uses it to his advantage. Meanwhile, London likes a boy so she pretends to be poor for him to like her.
Zack and Cody join the Wilderness Scouts with their leader being Mr. Moseby. Cody becomes jealous when Zack turns out to be a better outdoorsman. Meanwhile, London claims that Maddie stole her former boyfriend and both plead Carey for advise on her "relaxing" day.
When a hawk comes and lays her egg Arwin scares it away and somebody has to take care of it. Cody agrees, and he does a good job at parenting. Maddie tries to protest about getting rid of the bird.
Zack and Cody convince Mr. Moseby to open a club for kids in the hotel's lounge in which they would manage. London has her own line of cosmetics in which she needs help coming up with a name for it.
The twins compete on a game show in which Cody does the mental challenges, while Zack has to do the physical challenges. Maddie mistakenly sends Mr. Moseby an angry e-mail which she tries to retrieve.
Zack receives help for a history report from Mr. Moseby's grandmother, when she comes to visit. Meanwhile, Mr. Tipton forces London to get a job.
Zack and Cody go on a double date to a miniature golf course. Zack tries to impress his date, Ella, but things backfire on him. Cody and his date, Barbara Brownstein, have an intellectual attraction. London joins a bookclub with her rich friends much to Maddie's amazement. Carey tries to become a more healthy-living person.
When the Tipton holds Health and Fitness week, everyone begins to examine their eating habits. Cody helps Chef Paolo in an attempt to lower his cholesterol, while Carey begins to limit Zack’s sugar intake. Meanwhile, London and Maddie participate in a charity fashion show where they are both criticized about their looks, each taking drastic measures to change.
When a wheelchair basketball team visits the Tipton; Zack and Cody's basketball team plays an exhibition game against them. Meanwhile, Maddie is filming a movie for a student filming contest. She hires Lance, London and Mr. Moseby, but they're all terrible, so she has to figure out a way to make her movie a success.
When Zack and Cody get discovered by talent scouts the Tipton staff goes to Hollywood to go watch a pilot of Zack and Cody's lives being filmed.
Becoming Hollywood stars starts to go to the boys heads.
When Zack and Cody knock an ancient mummy over the balcony, Zack dresses Cody up to replace it for the exhibit. Esteban is scared of the curse of the mummy, so he and Maddie try to swap the mummy for Maddie's old doll.
Zack and Cody are not happy about their career aptitude tests. London gets jealous of Maddie when she saves someone's life and gets on television.
Zack and Cody wish for superhero powers when they see a shooting star. Their wish comes true and they learn that Mr. Moseby is their villain, who wants to turn all kids into miniature adults.
Zack gets a job at the minimart, but has to deal with Cody bossing him around. Meanwhile, London doesn't know how to present Lance to her friends.
London (even though she can't sing or dance) gets the role of Sharpay in their school production of High School Musical instead of Maddie because Mr. Tipton is financing the director's play "Floss" on Broadway. Zack has to work backstage for detention and Cody gets the part of Troy.
Zack tries to negotiate a better contract for Carey as the Tipton's nightly singer. Nia and London both want Cody's help with their science projects.
A monster-like robot is accidentally released into the hotel, due to the twins. A Halloween party is thrown by London. A typical prank.
Maddie is back and is not getting along with Nia, while Estaban is not getting along with Patrick, and the rest of staff aren't getting along either. So, Mr. Moseby hires a professional to help the team get along. Meanwhile, when Zack causes some customers to leave, he and Cody schedule a bug convention at the Tipton to make it up to Mr. Moseby. However, due to his fear of bugs, he accidentally releases the bugs into the Tipton.
Cody Martin is currently with Barbara, during music class there is a famous Russian violinist Sergei, and he starts flirting with Barbara. When one of the classmates starts a rumor that Barbara and Sergei are moving back to Russia and are going to sell llamas, Cody gets extremely jealous.
Zack and Cody each invite a girl over to their dad's empty apartment. Meanwhile, London teaches Esteban how to act rich because his family has seized power in his native country.
Cody helps London with her online video website. Meanwhile, Zack and Mr. Moseby become addicted to a certain video game.
Tony Hawk checks into the Tipton; Maddie and London has a crush on their fencing instructor. While Zack and Cody are doing their science project, the problem is that Cody has a fear of germs, and when Zack makes a mistake when analyzing a germ from the kitchen and thinks it's a toxic type of black mold, the rumor spreads through the hotel and everyone starts panicking. Cody gets over his fear after he realizes that he can't go skateboarding with Tony Hawk wearing an anti-germs suit.
Zack and Cody befriend Travis, a kid whom they rope into helping them impress their dates. They then bail on Travis and go out with their dates, but lets Travis go with the girls instead. Maddie finds a stranger's phone whom she thinks is her crush (because she and the stranger have many of the same interests, which she found out on the lost phone). At the end, the owner of the phone was an old man, but Maddie takes an interest in the old man's grandson.
Zack tries out for the high school basketball team but realizes there's some stiff competition, the kind he didn't face in middle school, and worse yet, the giant, in-your-face Coach Little (Michael Clarke Duncan). Meanwhile, when they're rejected as cheerleaders, Cody and London form their own cheerleading squad with the help of Mr. Moseby.
The twins take their mother on a vacation aboard the S.S. Tipton. Unbeknownst to her, however, they fail to inform her that she is the ship's singer.
Mr. Tipton comes to the hotel with the intention of firing someone.
Prince Sanjei comes to the Tipton to be crown king, but when he tells Zack and Cody he wants to try being a regular kid, Cody poses as him, and Zack takes Sanjei to the mall. Meanwhile, London thinks she saw a UFO, so she invites Maddie over to stay up and look for one. Maddie though, is in it just for the free food and service.
