A giant lizard-like monster emerges from an active volcano on a remote island, frightening the natives. They believe it to be an evil spirit of Monatabu, an evil witch doctor. When Samson and Goliath arrive at the village, the chief of the tribe tells them how they punished Monatabu by making him leap into the volcano. Ever since, his spirit returns every year to seek revenge. The boy and dog go into the volcano for investigation. Samson leaves Goliath, and finds the witch doctor is still alive. Not only that, but the monster is there, too, who is actually a prehistoric Iguanasaurus. Monatabu discovers Samson, and captures him by knocking him out with magic energy from his skull wand. Samson is then tied to a slab. Monatabu reveals that he befriended the Iguanasaurus when he entered the volcano. It is this beast that has been terrorizing the natives. Samson calls Goliath, who unties the ropes, and frees him. Then, Samson becomes the biblical strong man, and Goliath turns into a giant, Super Lion. When things get too tough, Samson uses Super Samson power to make himself and Goliath more powerful. Eventually, they seal Monatabu and the Iguanasaurus inside the volcano for keeps. When they leave, they tell the natives they no longer have anything to fear, and drive away on their motorcycle.
Upon their visit to Northpole, Samson and Goliath encountered a gigantic electrically charged monster manifested from the Aurora Borealis, and begin terrorizing an Eskimo village. With the combine efforts of Samson and Goliath, they saved the day.
The Colossus of Rhodes comes to life by a mysterious energy from some meteorites, and goes on a rampage. Samson and Goliath send it back into the sea.
An A.I pair of android robots from planet Venus arrives on their spaceship on Earth and begin to conquer human world by freezing it with their ice-rays to make the environment suitable and compatible for the Venusian race. When Samson and Goliath thwarts all of their attempts, then as a contingency plan, they initiate their mega-ice ray but again Samson and Goliath foil their plan by deflecting their freeze ray and melting them.
A group of terrorists are watching over monitor about the unveiling of the newly developed Super Sonic experimental transport plane called The STX-19. Their leader have a plan to dismantle the plane and ship it out of the country. For very same purpose, they intruded the top secret military area in a Crop-Dusting plane and renders everyone unconscious by the gas, including Samson and Goliath. In order to make sure that Samson may not come in their way, they slipped Samson's gold power bracelets with imitation of lead one, and finally steals away the STX-19. Goliath come into senses and awake Samson to discover the plane stealth. On their way to find the plane, Samson and Goliath are captured by the terrorists. Samson is put behind the bars, while Goliath succeed in eluding them. Soon Goliath found the real bracelets from the leader terrorist and brings them back to Samson, and capture the gang, and bring back the STX-19 to the military. However the title slide says the SXX-19.
A renowned scientist, Professor Talos is on his way to Pentagon with the plans of Solar Jet. Meanwhile, the agents of P.E.R.I.L, a criminal organization led by Monarch, the head of the organization follows the protocol of Professor Talos. When the Professor Talos' protocol knew the impending danger, they tried to elude them but P.E.R.I.L immobilizes the whole city's transport including cars, bikes, trains and even an Aeroplane with the strange waves. In state of stand still, an aeroplane was about to fall but Samson managed to transform himself on time and saved it from free falling by carry landing it on ground safely. On very moment, P.E.R.I.L succeed in abducting Professor Talos. Samson and Goliath follow P.E.R.I.L's aircraft and both jumps upon it to rescue Professor Talos. P.E.R.I.L saw them coming and tries to get rid of them by rotating the aircraft at different angles but then Goliath hits his paw to create a break-through the aircraft and enters. Upon their entry, the main gate gets closed with five heavy metal slides but Samson twists his bracelets to increase his powers and then ripped out all of the slide doors. They then encounter a pair of robots approaching them with weapons, but Samson throws a heavy rod at them that causes them to short circuit each other out and gets electrocuted. Samson and Goliath then advance to the control room, where Monarch tricked them to fall into his trap to face his most destructive weapon "The Living Element", an anthropomorphic fire monster. Goliath tried to repel The Living Element with his Power Beams and when the monster's extremely hot body touches the steel wall of the aircraft, it gets melted and the monster falls into the water and gets evaporated. Samson and Goliath then returns to the control room and are welcomed by the P.E.R.I.L agent with the LASER gun that Samson managed to blast off and then Monarch tries to eliminate them with the Solar Gun but Goliath whips him with his tail. Monarch falls back and accid
With help from a native named Maori, Samson and Goliath head for Evil Island to investigate the disappearance of a missile. After encounters with mechanical sharks, hostile natives, and a talking flame, they meet Boltor. Boltor launches fifteen missiles, but the heroes destroy them. Boltor pulls a switch that sinks the island, but Samson and Goliath escape just in time.
Samson and Goliath are teleported to an asteroid to deal with Zargo, an evil alien, and his robot army, the Monsteroids.
General Tong and Ramu send Rama-Keesh, a mechanical idol, to terrorize a village. Samson and Goliath break into their temple, destroy the idol, and defeat the villains.
In an undersea laboratory, three villains see a ship passing by. Salamandro, the ringleader of the trio, sends his henchmen to the ship to steal the gold bullion it's carrying. The men enter the transportation machine their boss has invented, and seconds later, materialize on the ship's deck. There, they paralyze the captain and his first mate. Then they go down to the vault, freeze the guard, and remove the gold. One of them sends a signal to Salamandro to let him know they have the loot. He brings them back, and gloats over the successful theft. Sometime later, Samson and Goliath are on a ship carrying a crate load of paintings. The captain expresses concern that the art will be stolen. The heroes go into the vault via a funnel, and hide themselves in the crate that holds the paintings. Salamandro sees the ship go by, and sends his goons directly to the vaults so they won't be seen by anyone. They find the crate, and send another signal. When they open the crate, they are surprised to find Samson and Goliath inside. When the duo transform, the henchmen try to paralyze them, but Goliath melts their guns with his power beams. Salamandro traps the pair inside a steel trap, but Goliath uses his roar to break them out. Noticing that their enemies are gone, Samson and Goliath head for an iron door, but are momentarily stopped by the electro rays that appear on it. Samson lifts the door without touching the rays, and he and Goliath enter the next room. Salamandro is there, but he's behind a glass shield that the heroes can't penetrate. He explains that it's eight feet thick. Then another glass shield appears behind them, and a deadly mist is pumped in. Samson and Goliath escape by crashing through the ceiling. One of the accomplices fires a ray through a hole in the wall, and successfully immobilizes Goliath.
Samson and Goliath meet Baron Von Skull, a former World War One flying ace from Germany.
Kunev Kahn steals the Graviton. Samson and Goliath sneak aboard his space ship, and find themselves on the moon. There, they deal with both Kunev Kahn, and his partner in crime, the Moon Leader.
Samson and Goliath enter an underground city to rescue Professor Kinkaid from the Dragon Men.
A pair of criminals based in a lighthouse revive a coral monster. It attacks an Australian city. Samson and Goliath defeat it. It destroys the lighthouse and returns to the sea.
Samson is temporarily weakened when Dr. Zuran transfers his super strength to a robot.
Samson and Goliath prevent the Dome from launching his deadly missiles.
Samson and Goliath pit themselves against Nerod's gladiators.
The appearances and disappearances of a Tyrannosaurus, Cyclops, and Rok, send Samson and Goliath to Dr. Desto's laboratory. He uses his time shield to bring in a variety of menaces from the past. Finally, he sends out a plague of locusts. Samson and Goliath drive the insects back. They are pulled back into the machine, but so is Desto. Samson then destroys the time shield for good to prevent Desto from ever returning.
Samson and Goliath's vacation is interrupted by the Gill Men.
A missile arouses a creature from the water near the Black Mountains. Samson and Goliath stop its rampage, and send it back to its environment.