In the series finale, Jonathan's guests include the Emmy, Grammy, Oscar and Tony Award-winning John Legend - who will be performing in the studio - and actor Jeff Goldblum.
| Name | Type | Role | |
|---|---|---|---|
| Jonathan Ross | Writer | ||
| James Farmer | Writer | ||
| John Legend | Musical Guest | ||
| John Legend | Guest Star | ||
| Lee Mack | Guest Star | ||
| Jeff Goldblum | Guest Star | ||
| Jack Whitehall | Guest Star | ||
| Shirley Ballas | Guest Star | ||
| Chris Howe | Director |