Jonathan's guests this time include Gavin and Stacey star and co-writer Ruth Jones and Buffy the Vampire Slayer herself, Sarah Michelle Gellar.
| Name | Type | Role | |
|---|---|---|---|
| Jonathan Ross | Writer | ||
| James Farmer | Writer | ||
| Annie McGrath | Writer | ||
| The Molotovs | Musical Guest | ||
| Sarah Michelle Gellar | Guest Star | ||
| Alison Hammond | Guest Star | ||
| Ruth Jones | Guest Star | ||
| Kathryn Newton | Guest Star | ||
| Richard Ayoade | Guest Star | ||
| Chris Howe | Director |