Bob is a married advertising executive who enjoys picking up women throughout his travels. After picking up the Hitchhiker, he runs into a beautiful blonde who he ends up spending the night with. After hearing a report on the radio that there is an escaped blonde mental patient named Ann Marie Brown on the loose who enjoys slitting men's throats, Bob becomes convinced that the woman he picked up is really the escaped mental patient, but things are not always as they seem.
John 'Jake' McElhaney will do anything to make a sale, absolutely anything. Faced with losing his job, he decides to make his next sale really count, and thinks he has it made when he signs on to work for the Packard twins, two women who have problems sharing and so split everything directly down the middle. Frances makes it clear straight away that she likes Jake, but Jake also plays up to Priscilla, hoping to not only sell the house for the two women but sell each of them homes as well. Unfortunately, the bond between the sisters is stronger than any bond they could form with him.
For months, Eric Dunlap has been hard at work on a special sound system for Kurt Hoffman, a temperamental conductor who is impossible to please. During that time, he fell deeply in love with Hoffman's much younger wife, Veronica. It isn't long before Eric realises the computer he created, which only responds to him, is something special. When Veronica realises she returns Eric's feelings and the two become lovers, Hoffman learns of his wife's infidelity and exacts his revenge on the two, but Eric's creation avenges the man who gave it life.
Mickey is a con artist only willing to commit to one way of thinking: making the quick buck. In exchange for his life, Mickey is willing to sell his soul by giving Pearl, his girlfriend, away to drug lord, Joey Stregga. What Micky doesn't realize is that he will have to pay for selling off part of his soul.
Jack Rhodes is a salesman that attempts to wear many disguises to get what he wants: women. One day, he gets a video letter from a mysterious video-artist, Monique, who challenges him to meet her. She plays him like a fiddle and takes advantage of him. Now the tables are turned and Jeff can't escape, not even with his life.
Rae Bridgeman is caught up in a love triangle with her husband Lew and his best friend Joe. Lew finds out about their affair and decides on a late night hunting trip for all three of them. Instead of killing Joe, he accidentally kills Rae. In a panic, they drive away from the scene only to find themselves in a deadly accident.
An ex-drug addicted screenwriter Arthur Brown steals the life and words of Diane Hampton. Diane is struggling to maintain her marriage with her abusive jealous husband John and to keep the affair with her female lover Cathrine a secret. Arthur tips John off about Diane's affair and soon finds himself the target of John's anger.
Kay Mason is an abusive owner of a dressmaking sweatshop. One day she is cursed by an angry worker who exclaims that she will be paid back by the devil for her actions. When Kay hires a mysterious stranger to do some odd jobs around the house, she doesn't realize that she has hired a devil in disguise.
Dr. Peter Milne, an unethical psychiatrist, abuses his position to manipulate a female patient. His mind-bending medical practices only intensify her psychosis as she can no longer distinguish reality from dream. When he finally has her act out her dreams, Dr. Peter Milne finds himself the victim of her murderous feelings.
A young man on the run from the police takes refuge in a mysterious building where a bizarre woman, Angelica, torments him with visions of his past life while another woman tries to help him. Condemned by jeering circles of audience members, the young man is jeered on to give one final performance...only to wake up to find he is on the verge of death on an operating room table. He is at St. Angelica's Hospital, and the statue of the woman looks strangely familiar.
Reverend Nolan Powers is a money hungry radio evangelist preaching on the air waves about the bible. 0ff the air, he's a self-righteous greedy man. A tabloid news reporter, Sato, digs up the story about how the Reverend killed his brother, Gerald. Gerald's ghost comes back to haunt the Reverend, ruin his career and pay him back for causing his death.
Rat witnesses a group murder among feuding drug dealers, steals the drugs from the dead bodies and leaves the scene of the crime. The Wise Man and The Fool find her laying dead and take the package of cocaine. Unbeknownst to all of them, Mr. Big, the original owner, sends his henchmen out to retrieve it at any cost.
Claudia now a famous novelist, returns home for her high school reunion and opens old wounds in Lee, the sheriff. Claudia finds out that Lance, her town-appointed escort, is really the son of a former high school boyfriend who blames her for his father's death. Fighting over her, Lance and Lee replay the fateful event that killed Lance's father, but this time, it is the sheriff who loses his life to Dead Man's Curve.
Jerry Maclachlan is the owner of a rundown apartment building who promises Serita, a tenant, that he will make repairs to the building. After he becomes involved with a strange woman Tanya, he discovers a snake tattoo on his body. Both Serita and Tanya tell him how to get rid of the snake. He realizes that the two women are the same person.
A non-believer in the supernatural, Detective Frank Sheen must investigate a priest's suspicious suicide. Upon questioning Father Dowling he learns that the convent is demonically possessed. Unbeknownst to the detective, the site used to be a convent that closed down when a Sister Theresa committed suicide. After one night in the place, he soon begins having his own suicidal feelings.
Jill McGuiness is a lonely daydreaming bank officer who constantly fantasizes about her dream lover. When she dreams about murders and finds that they actually happened, she is unable to distinguish dream from reality. When she finally meets Mr. Right, Jim, she snaps out of her dream world and catches him.
Jane L. is willing to dig up anything on someone just to ruin their lives and get her a story. One night, her photographer gets her interested in Billy Baltimore, a musician who supposedly died back in the 70's but is rumored to be living in their area. But soon Jane realizes that when you enter someone's life, you should always make sure there's an exit.
Cheryl and Bruno are con artists who believe the world owes them something. When they face homelessness because the building they live in is about to be torn down, they find a new mark, Emilie Langlois, an old woman with a failing memory. Their goal is to take over Mrs. Langlois' home, but they soon realise that some memories are best left forgotten.
Men in the city are being knifed by a prostitute who wears all black. Sterling Jenkins is a hard-hearted prostitute who, despite herself, is intrigued when an attractive man named Jason asks for help in fixing his car. Although she tries to rebuff the sensitive man, Sterling allows herself to believe Jason when he tells her that he's fallen for her. It is only afterward that she realises appearances can be deceiving.
After the suicide of their friend Katie, Adam Ross and Stephanie Duvall are faced with their own mortality. They learn from a friend, Brian, that he believes Katie was murdered, and that it had something to do with a fortune teller she had gone to see. Adam and Stephanie visit the same fortune teller, a woman who has let herself become so bitter she taints the life of everyone she comes in contact with.