Jeremy the Germ gets a visit from his brother Nigel, who wants to turn him back to his old bad-guy habits. Will Jeremy be able to resist that and stay loyal to Talking Tom and his friends?
La vie de Tom, un drôle de matou, rythmée par de nombreuses pitreries, en compagnie de son élégante petite amie, Angela, de son jeune neveu coquin, Ginger, et de ses bons copains, les chiens Ben et Hank.