Amy, a 44-year-old mum, is confronted with a life-changing diagnosis of a rare abdominal cancer, which was only discovered by chance when she was trying for a second baby.
Single mum Tracy faces a life-and-death battle with a rare and aggressive brain cancer. And we meet Kylie, who's revolutionising emergency stroke care.
When Kyle's first kidney transplant from an organ donated by his brother fails, he gets a second chance at life when his sister Jess offers to donate one of hers.