This parody of Stanley Kubrick's 2001: A Space Odyssey features Joel Hodgson, creator of Mystery Science Theater 3000, and comedic magicians Penn and Teller. Moltar and Zorak are fired when Space Ghost replaces them with MOE 2000.
| Name | Type | Role | |
|---|---|---|---|
| Evan Dorkin | Writer | ||
| Sarah Dyer | Writer | ||
| Teller | Guest Star | ||
| Penn Jillette | Guest Star | ||
| Joel Hodgson | Guest Star | ||
| Keith Crofford | Guest Star | ||
| C. Martin Croker | Director |