The story of the Jamestown settlement, the first permanent English colony in the Americas, is seen through the prism of a 14-year-old English girl whose skull and severed leg were discovered during the excavation of the trash layer of a cellar. The study of her remains reveals evidence that one or more of the settlers, who endured a 1609-10 winter that's often called the "Starving Time," resorted to the unthinkable—cannibalism—to feed themselves.