In this introductory lecture, we define the basic terms of the course, its content, methodology, and focus. This course deals with the interactions of Christianity with science in the Western world over a long time span. We also look more closely at the terms science and religion in order to prepare ourselves for consistent discussions in future lectures. Finally, we look briefly at the various models for the interactions of science and religion that have been proposed, critique them, and provide some pointers for engaging with the balance of the course.