John Mulaney hosts Saturday Night Live on February 26, 2022 with musical guest LCD Soundsystem.
| Name | Type | Role | |
|---|---|---|---|
| LCD Soundsystem | Musical Guest | ||
| John Mulaney | Host | ||
| Al Roker | Guest Star | ||
| Steve Martin | Guest Star | ||
| Paul Rudd | Guest Star | ||
| Conan O'Brien | Guest Star | ||
| Candice Bergen | Guest Star | ||
| Tina Fey | Guest Star | ||
| Elliott Gould | Guest Star |