Sketches include: Hot Ones, Boomers, A Kamala Harris Unity Seder, NFTs, Weekend Update, Richard Perquest & Tanya Katank, 2021 Barfly Awards, The Maya-ing
| Name | Type | Role | |
|---|---|---|---|
| Jack Harlow | Musical Guest | ||
| Adam Levine | Musical Guest | ||
| Maya Rudolph | Host | ||
| Martin Short | Guest Star | ||
| Tina Fey | Guest Star | ||
| Rachel Dratch | Guest Star |