John Mulaney hosts, and Chappell Roan performs.
| Name | Type | Role | |
|---|---|---|---|
| Chappell Roan | Musical Guest | ||
| John Mulaney | Host | ||
| Dana Carvey | Guest Star | ||
| Tim Kaine | Guest Star | ||
| Maya Rudolph | Guest Star | ||
| Pete Davidson | Guest Star | ||
| Andy Samberg | Guest Star | ||
| Kamala Harris | Guest Star | ||
| Jim Gaffigan | Guest Star |