At the American Museum of Natural History, creepy crawly arachnids and insects serve as inspiration for the designers to create an avant-garde look. Guest judges are Project Runway season 9 winner, Anya Ayoung Chee, and jewelry designer Jennifer Meyer.
| Name | Type | Role | |
|---|---|---|---|
| Anya Ayoung Chee | Guest Star | ||
| Jennifer Meyer | Guest Star | ||
| Michael Pearlman | Director |