"Brain" for short looks and sounds a little like Orson Welles. In "What Ever Happened to Baby Brain", Brain actually crosses paths with Welles, who is working as a busboy in a Hollywood restaurant, and they find themselves inadvertently yelling in unison, "Things will be different when I take over the world!" In "Project B.R.A.I.N.", Brain's name is the backronym for the eponymous project: "Biological Recombinant Algorithmic Intelligence Nexus".