Kyoto University's Center for iPS Cell Research and Application (CiRA) celebrates their 10th anniversary in April 2020. Professor Shinya Yamanaka, who developed the method to produce iPS cells, serves as the director for the center. How much progress have they made in the past 10 years toward clinical application? What vision does the director have for CiRA for the next decade? The program looks at how Yamanaka runs the organization as well as the past and future challenges of CiRA.