Simon's twin brother, Sedrick, seizes control of Jurassic World and installs an artificial intelligence system named "O.O.P.S.I.", turning Jurassic World against all humans! Owen's team works frantically to keep everyone safe, while trying to figure a way to shut OOPSI down. Meanwhile, Dr. Wu has been working on two eggs containing a new, more aggressive dinosaur but Robbie, Simon's intern, makes off with the dinosaur eggs. Claire, Dr. Wu and others set off in pursuit, but only catch the thief after the eggs have hatched and the fierce twin dinosaurs have escaped into the jungle near the Park!
Katala rosvo anastaa Jurassic World -puistosta kaksi munaa, joiden sisällä kasvaa uusi dinosauruslaji! Tässä olisi jo ongelmia kerrakseen, mutta lisäksi puistoa johtaa täysin kelvoton tekoäly, joka vain mutkistaa tilannetta.