Seth recruits Amber Ruffin and Jenny Hagel to help him deliver jokes in a new Jokes Seth Can’t Tell, interviews Natalie Portman about her new children’s book Natalie Portman’s Fables, chats with Cindy McCain about the 2020 election and welcomes Dave Matthews for a performance of “Mercy.”
| Name | Type | Role | |
|---|---|---|---|
| Natalie Portman | Guest Star | Guest | |
| Cindy McCain | Guest Star | Guest |