Ozu decides to take a vacation- his first in several decades. Before going, he reads off a long list of rules- most importantly, not to harm his prized 500-year-old Bonsai tree. Of course, even before he reads this, Mikey accidentally sets the tree aflame. Now, Mikey and most of the gang (excluding Lily, who is their temporary boss, and doing all she can to keep them busy) must work to replace the Bonsai before Ozu gets back from his unusually short vacation.
A new Kappa Mikey game is released and Mikey goes berserk trying to get a copy. In Mikey's absence, Lily is getting swept into the charm of Suave Mikey, a Mikey look-alike, whom they mistake for the real Mikey. However, Mitsuki is quite suspicious- does Mikey really have a car, a boat, and memories of a trip to Venice?
Mikey throws away Mitsuki's treasured photo album after learning the joys of recycling. Eventually, Mikey recovers it only to discover that all the photos have been removed. Now he must somehow get them back... or create new ones in hopes of fooling Mitsuki. Meanwhile, Gonard and Lily are thrown into a relationship by Ozu to stir up publicity, only to have Guano interfere and make a love triangle. Who will win Lily's heart? Will it be Guano or Gonard? Only a duel can solve this!
Mikey finds a cute little kitten and adopts him as a way to gain more popularity. The plan backfires and the entire media forgets about Mikey and focuses on the cat who becomes Japan's newest star and costs the LilyMu cast their jobs. Trying to get rid of the cat, Mikey hires a cat burgler, one that eats cats. Meanwhile, Ozu's plans to open a LilyMu superstore run short when he adopts the cat away from Mikey and fires the LilyMu cast. The LilyMu superstore is now changed to the a Kello the Kitten store.
When Mikey finds out his childhood hero Captain Impressive is reduced to a bad show at Tatami Megastore, he is devastated. So Mikey changes his image to a bad boy in fear of the same fate. Meanwhile, Mitsuki gets dating advice from Lily and is shocked when she learns that Mitsuki's crush is really Mikey.
After not being able to lift a prob while on set, Mikey decides to go to a gym and get stronger. A sumo named Yokuzuna becomes Mikey's newest rival and a mysterious trainer helps Mikey in defeating him. On a tennis court, Gonard is working on his game until he is embarrassingly defeated by the ball machine. When the rest of the cast asks what happened, he describes an assailant that sounds exactly like the ball machine.
While horsing around, Mikey and the gang discover a secret floor in LilyMu Towers. Inside, they find a mad scientist and his enlarging ray. Gonard gets hit with the ray and now its up to Guano to use it on himself and defeat MegaGonard.
After coming across a bunch of musical instruments in the audio booth, the gang decides to start a band. Unfortunately, they are really bad. When Ozu listens however, he mistakes Mikey's cell phone ring tone for their music and turns "LilyMu" into an act to take advantage of their musical prowess. They go along with the lie for a bit until a group of girl rockers call them out. Then it's time for a Battle of the Bands.
When Mikey feels like Ozu doesn't need him he is tempted to go back to America. The night before his flight, Mikey is visted by his guardian Angel. They show him what his castmates lives would be like without him. Meanwhile Ozu is visited by the ghosts of Japanese Christmas to try and show him the error of his ways.
Mikey Simon is trying to make his mark in showbiz in his hometown of Cleaveland, Ohio. Down on his luck, he comes across a scratch-off ticket and ends up winning a trip to Japan to star on the once great anime "LilyMu." Time will tell wether Mikey will become Japan's next big star or its next big flop
A reporter from Mikey's hometown of Cleveland comes to the set. When doing the story on Mikey, he deceives the reporter to make himself seem more important. Now his parents are coming to visit because of the story and Mikey must convince his friends to play along. Meanwhile Ozu and Yes-man try to create a weather machine for a mysterious reason.
Ozu gets a vist from Brozu, his cool and irresponsible brother. Because he was born first, he owns 51% of "LilyMu" and decides to run things. He ends up firing his own brother Ozu and making Mikey the producer. Now the cast must learn to deal with Mikey's unusual management style or wind up fired themselves.
When the gang goes to Mount LilyMu, everyone but Mitsuki can go on the bullet train, since Mikey cannot find Mitsuki's ticket. On the train, Mikey hears mumbles and finds Mitsuki tied up. Mikey convinces the gang to help find Mitsuki, and whoever kidnapped Mitsuki. In the subplot, Yes Man quits after a fight with Ozu.
Ozu and his crew go undercover as students and faculty at the local Lebaniku High School, in order to figure out who’s behind a DVD piracy ring, making illegal copies of their show. Mikey, unable to fit in with any of the cliques, winds up with two nerds. Gonard becomes the Lebaniku football teams’ secret weapon against their rival.
A pair of mystical friendship bracelets magically switch Lily and Mitsuki’s bodies, and they agree to live the other’s life for a while, so Mistuki can finally date Mikey. Lily ends up working with a pair of environmentalists named the Do-Gooders. In the subplot, Gonard and Guano are cursed by a tiki idol.
Mikey opens a Kappa Mikey-themed restaurant, which does lousy until Gonard starts preparing dishes for it. A rival restaurant nabs Gonard and hypnotizes him into making dishes for them instead. In the subplot, Lily is caught showing hatred toward babies, so Ozu forces her to take care of a baby for one day to regain LilyMu’s reputation.
Mikey gets lost in Yoyogi Park and meets a Werepuff, a monster who eats peoples' clothes, and Mikey turns into one when his pants are eaten off. Lily feels suddenly attracted to him, and they soon become a celebrity couple. The only way to cure him is if he eats the fur of the original Werepuff before dawn.
Like the heroes of the famous Japanese film The Seven Samurai, the cast responds to a distress call from a poor boy and LilyMu fan named Riku, whose playground is about to be destroyed by an evil Garbage Man to make way for a landfill. However, used to doing live shows, the five are under the impression that this is just another gig, and Riku thinks they are real heroes instead of actors.