Saba has fallen four floors from a balcony and the prognosis does not look good for the kitten. Young cat Lola is stuck up a chimney after moving to her new home. Plus, the tale of adopted Maine Coon cat Thula, who has changed the lives of one family forever.
Animal welfare officer Matt finds an injured young male cat that has lost its tail. A concerned member of the public calls inspector Anthony about a cat in her shed. Lovable tom Bruce has problems with his teeth.
Inspector Anthony rescues a cat who has given birth under a disused cabin. Cat Chloe has been stuck up a tree for five days, and Jo meets a woman who runs a cat sanctuary at her home.
Inspector Herchy is worried about the welfare of a young black kitten. Veterinary nurse Eden is looking after tiny kitten Pumpkin, while inspector Keira follows up on a call about an injured feral cat called Esme.
Jo meets two black rescue cats that have bagged themselves a potential new owner and she gives a hearing test to four blue-eyed white kittens.
Jo spends Christmas morning at Laybourne animal centre and finds out exactly what happens there over the Christmas period, before playing Santa to the cats.
Jo follows teams who work to save the nation's cats from harm, including 20 firefighters who try to help a kitten stuck in a storm drain. She also visits RSPCA Harmsworth in north London, where she meets a cat who survived falling more than four storeys. In Liverpool, RSPCA officer Paul gets an emergency call about a cat tied to a fence.
Animal welfare officer Matt Brown receives a call about a family of kittens hiding in the loft space above a shop. However, the rescue does not quite go to plan, leaving one little kitten in a sticky situation. Inspector Anthony Pulfer goes to extreme lengths to save a stray tomcat from an inaccessible courtyard in a busy building site, and Jo visits RSPCA Putney, where she meets a kitten with a crushed paw and helps test a feral ginger cat for a potentially life-changing virus.
Animal welfare officer Matt Brown is sent to pick up two cats trapped in a squalid property that has been abandoned by squatters, while in Birmingham, RSPCA inspector Herchy Boal investigates a report about a neglected cat with a broken leg. Jo returns to Putney Animal Hospital, where she assists vet Ellie Cavale with a kitten castration.
Animal collection officer Joe White faces a high-risk rescue when a kitten is spotted on a motorway hard shoulder, with cars roaring past just metres away from the frightened feline. Inspector Sam Durrant visits an owner who has been reported for keeping his animals - and himself - in unhygienic conditions, and Jo revisits young Stanley to see how his crushed paw is healing.