Annalise Keating is everything you hope your Criminal Law professor will be - brilliant, passionate, creative and charismatic. She's also everything you don't expect - sexy, glamorous, unpredictable and dangerous. As fearless in the courtroom as she is in the classroom, Annalise is a defense attorney who represents the most hardened, violent criminals - people who've committed everything from fraud to arson to murder - and she'll do almost anything to win their freedom. Each year, Annalise selects a group of the smartest, most promising students to come work at her law firm. Working for Annalise is the opportunity of a lifetime, one that can change the course of our students' lives forever, which is exactly what happens when they find themselves involved in a murder plot that will rock the entire university.
Annalise takes on a new client, Max St. Vincent, an eccentric millionaire who is the key suspect in his wife's brutal murder. All the clues point to St. Vincent as the killer, but Annalise challenges her students to prove he's innocent - whether that's the truth or not. Meanwhile, Annalise deals with issues in her own home when her growing suspicions that Sam is somehow involved in Lila's disappearance start to affect their marriage. In flash forwards, we go back to the night of the murder and learn that Wes might be hiding a few secrets of his own.
Annalise helps Paula Murphy, a suburban soccer mom, get released from jail after she was arrested for a misdemeanor, but just as she’s about to walk free, she’s arrested again by the FBI in connection for felony murder. Annalise and her students are tasked with proving her innocence which will depend on the testimony from another suspect in the case. Meanwhile, the Middleton University president asks Annalise to represent Griffin O’ Reilly, the star quarterback who has also been linked to Lila’s disappearance but she’s unable to make a decision until she knows that Sam wasn’t involved in the case. In flash forwards, more clues are revealed and we discover someone else was also there besides the students during the night of the murder.
Annalise and her students uncover a shocking truth while investigating the case of Marren Trudeau, founder and CEO of a major brokerage firm, who has recently been arrested for insider trading. Meanwhile, Wes discovers a cell phone hidden by Rebecca whose contents reveal an unsettling clue in the Lila Stangard murder case.
Annalise takes on a tough case defending a minor who fatally shoots his police officer father. Meanwhile, Annalise and Sam continue to argue over his relationship with Lila, and Wes and Rebecca begin to question Annalise’s motives. In flash-forwards, we learn more about Laurel’s relationship with Frank and why he was calling her the night of Sam’s death.
A case gets personal for Annalise and the team when their client is a man from the projects who was sentenced to death by Asher’s father several years ago. Meanwhile, Wes is still angry at Annalise for hiding information about Lila’s case, so Annalise must convince him to get back in line. In flash-forwards, we find out exactly where Asher was on the night of the murder.
School is back in session after the holiday break and the entire university is talking about Annalise's missing husband. The Keating Five continue to be questioned by the police and we find out exactly how they've been dealing with the guilt of killing Sam. Meanwhile, Annalise tries to keep things business as usual by taking on a new client who is in the mob, but Hannah continues to pressure her for answers.
In flashbacks, we start to piece together what really happened the night of Lila's murder. In present day, Annalise takes on a priest who is accused of murdering another priest. Meanwhile, Connor and Oliver take things to a new level in their relationship, and Wes and Rebecca continue to grow suspicious of each other.
Annalise and her students must move on with their lives as though nothing has happened, but the students are still reeling over Rebecca’s disappearance. Only Annalise and Frank know that Rebecca was murdered and the two are determined to find out who killed her. Annalise decides she wants to take on a new client, a brother and sister who are accused of killing their parents. An old friend surprises Annalise at home and teaches her a valuable lesson.
With Wallace Mahoney’s murder unsolved and Frank’s whereabouts unknown, the ”Keating 5” struggle to move on with their lives as they enter into their second year of law school. Meanwhile, Annalise’s reputation at Middleton University is on the line, so she creates a criminal law clinic where the students will compete to try their own pro bono cases. Annalise also wrestles with a decision involving Frank that could change everything.
In the wake of Wes’ tragic death, Annalise returns to her family home to pick up the pieces of her shattered life, and realizes that, in order to rebuild, she must make a tough and shocking decision. The “Keating 4” all face an uncertain future while Laurel becomes obsessed with finding out what actually happened to Wes the night he died. In a flash-forward, a terrifying crime is committed and everyone is a suspect.
Annalise takes on a case for the greater good and quickly realizes the stakes are much higher than she originally thought. Laurel asks Michaela to help get information regarding Wes’ death and Connor makes a major life decision that is not supported by the group. In a flash-forward, a surprising confrontation during the night of the crime is revealed.
The events of Annalise’s class-action case hang in the balance after a meeting with Olivia proves to be crucial in getting the opportunity to argue Annalise’s case in the nation’s highest court. Bonnie discovers concerning information pertaining to Simon that threatens to expose what really happened during night he was shot. The crossover starts on Scandal S7E12 Allow Me to Reintroduce Myself (I).
Annalise receives a call from Governor Birkhead, and she’s forced to weigh an interesting offer, while Bonnie reunites with her sister looking for answers from what happened years ago. Connor and Oliver try to keep their cool while their mothers are in town helping with wedding plans, and Tegan surprisingly enlists Laurel’s help on a big case at the firm.
Annalise struggles with the personal toll that Laurel and Christopher’s disappearance has taken on everyone. Meanwhile, the remaining Keating 4, Oliver, Frank and Bonnie disagree on the possible reasons behind Laurel’s disappearance. Tegan handles the aftermath of Emmett’s apparent poisoning, and Gabriel wants to take his budding relationship with Michaela to the next level.
As Michaela, Asher and Connor gear up for their last semester of law school, they take on a weighty case involving an illegal immigrant who wants asylum. Meanwhile, Michaela boycotts going to class after a blowup with Annalise about her father. Elsewhere, in an unexpected confrontation, Annalise learns a shocking truth that makes her question everything she thought she knew.
After Michaela’s courtroom tactics do more harm than help, Annalise draws on memories of Sam to guide Michaela back to the winning path. Connor bites off more than he can chew in his effort to reunite a family, forcing Tegan to call in a favor and fix his mess. Frank enlists Oliver’s help to follow a lead on Laurel. Gabriel learns new information about Michaela’s birth father.
The FBI continues to interrogate Connor which leads him to panic under the pressure. Annalise, Tegan and the students defend a woman accused of violating a disabled man’s civil rights for developing a dating app that discriminates against him. Bonnie helps Nate get more intel on Tegan. Michaela and Gabriel travel to New York to track down her father.
During therapy, a young Annalise is forced to acknowledge a very emotional and pivotal reality that makes her admit a hard truth. A brutally beaten Frank returns home with a secret to share about Laurel’s disappearance. In an attempt to get to know her father, Michaela accepts an offer to work alongside him but quickly learns that it’s not all that it’s cracked up to be.
Annalise intervenes in Michaela’s relationship with her father and asks for his help in return. Because Nate still doesn’t trust Tegan, he attempts to get in good with someone who was once close to her. After Asher reunites and has an unpleasant conversation with his estranged mother, he shares a meaningful moment with Michaela. Connor finally learns why he was originally picked for the Keating 5.
After taking the stand during Nate Senior’s murder trial, Bonnie’s world is turned upside down when a mysterious accident leads her to a hard realization. The students compete for a large cash bonus during the final exam where they must come up with the best defense for a conspiracy-to-murder charge.