Things could not be better between Jac and Jonny, but when she hears that the former 'love of her life' is getting married, she is thrown and jeopardises everything that she cares for. Serena is running Holby like clockwork, but can she hold onto her position even when under threat from a competitor? When Chrissie finds a lump, she is afraid for her health but is reluctant to confide in Sacha.