The sixth season of High Stakes Poker starts with Phil Ivey, Andreas Hoivold, Phil Hellmuth, Gus Hansen, Tom Dwan, Dario Minieri, Antonio Esfandiari, and Daniel Negreanu playing $400/$800 No-Limit Hold'em on High Stakes Poker.
| Name | Type | Role | |
|---|---|---|---|
| Gabe Kaplan | Host | Himself - Commentator | |
| Kara Scott | Host | Herself - Commentator | |
| Dario Minieri | Guest Star | ||
| Gus Hansen | Guest Star | ||
| Phil Hellmuth | Guest Star | ||
| Phil Ivey | Guest Star | ||
| Andreas Hoivold | Guest Star | ||
| Antonio Esfandiari | Guest Star | ||
| Tom Dwan | Guest Star | ||
| Daniel Negreanu | Guest Star |