Once-successful patent attorney Harriet Korn is fired and decides to begin anew with her own practice. With the help of her happy-go-lucky assistant, Jenna, she sets up shop in an abandoned shoe store in a rough section of Cincinnati. Her first case is to defend Malcolm Davies, a troubled young man, facing his third drug offense. Meanwhile, up-and-coming attorney Adam Branch joins the firm, and defends a "private security officer" after he shoots a man who is attempting to rob a laundromat.
Harry defends an impoverished 87-year-old woman who commits armed robbery to buy food. Meanwhile, in an attempt to impress a beautiful woman, Adam takes on an unlikely case in which he must argue in favor of a laundromat owner's strict "one-child only" policy for his employees, but is shaken when opposing counsel is none other than flamboyant media hog Tommy Jefferson.
After getting a tip from a priest, Harry helps defend Jeffrey Rollins, an inmate serving life for a murder he did not commit. Meanwhile, legal woes continue to worsen for the laundromat after Adam risks disbarment by going behind Tommy’s back to offer the fired employee her job back. Elsewhere, Malcolm and Tommy form an unlikely partnership when they team up to help an overweight woman sue multiple fast food giants.
Harry grows increasingly concerned about Malcolm’s association with the over-the-top Tommy and their lawsuit. Meanwhile, Tommy struggles to be less ridiculous as he, his associate, and Malcolm argue in court against large fast-food corporations. In a shocking turn of events, Chunhua is attacked behind the laundromat. When her assailant is set free after cutting a deal, Damien risks serious jail time by taking justice into his own hands, while Adam finds comfort in his ex-girlfriend, Rachel.
When Harry discovers her client is guilty, she proclaims his guilt in front of the jury when she is not allowed to quit the case. The judge has no choice but to find Harry in contempt and recommend her for permanent disbarment. Meanwhile, Malcolm goes undercover with Cincinnati’s finest in exchange for an expunged criminal record.
Tommy convinces Harry to help him defend four albinos seeking asylum in the U.S. from the dangers of albino hunters in their native Tanzania. Elsewhere, Jenna's car is stolen, but is later returned by the thief's sister in hopes that the firm will represent him on an unrelated theft charge. Back in the office, Jenna and Harry's relationship gets rocky when Harry makes a hurtful comment.
Malcolm has gone off to college and Harry and Tommy decide to share the office space above the shoe store, which Jenna will continue to run. Harry is asked, by an attorney from her previous law firm, to defend a man accused of killing his wife. The District Attorney herself tries the case and will go to any length to win.
Harry teams up with Ollie to defend a teenage blogger who is arrested when a classmate commits suicide shortly after being outed in the blog. Adam takes Tommy to court for accepting a life insurance policy as payment from a now-deceased cancer patient. All the while, Jenna weighs a tempting job offer that could take her away from Harriet's Law & Fine Shoes.
Harry and Adam defend former prosecutor Josh "Puck" Peyton, who stands accused of aiding and abetting a kidnapper; Peyton successfully negotiated her safe return, but did so behind the back of the FBI. The case brings Harry into a fierce rematch with D.A. Roseanna Remmick who is back with a vengeance and determined to outdo Harry and put Puck in prison. Elsewhere, Tommy ropes Cassie into an ethically questionable divorce proceeding involving his oldest clients.
While Harry is on vacation, her trip takes a frustrating turn when the small town of Langford, Ohio impounds her Mercedes Benz for violating their "Buy American" law. Harry, with Oliver at her side, challenges the town's law and is pit against a young, homespun attorney and the engine behind the law, Langford's mayor, Franklin Chickory. Meanwhile, Adam represents the Chens, a Chinese family whose daughter was stolen because of China's one-child policy and adopted by American parents. With Cassie's help, Adam hopes to win custody for the Chens.
Harry must practice some conflict resolution when Oliver and Cassie butt heads over an emotional case: defending a schizophrenic 17-year-old who shot and killed three college students on campus. Meanwhile, Tommy represents an owner and operator of two businesses: a "Green Mortuary" for eco-friendly burial, and an organic produce market. Unfortunately, his two businesses overlap resulting in his vegetables being fertilized with the decomposing bodies. Elsewhere, Chunhua (Irene Keng) returns to ask Adam (Nate Corddry) for help when her family's dry cleaning business is seized through eminent domain in an effort to "develop" the neighborhood.
Jimmy, a dear friend of Harry’s, comes to town with more than just a good hand of poker, but a plea to help him change the law regarding the sale of kidneys, as he recently found out he only has six months to live. As hard as they tried to prove it was no different than the sale of semen or blood, the judge refuses. Oliver and Tommy defend twins, Laila and Nicole accused of killing their husband with Hoseanna Roseanna prosecuting. When Nicole admits to the crime, Tommy and Oliver attempt to point the finger at each other’s clients which results in both Laila and Nicole’s conviction in the crime, despite Laila’s innocence.
Harry walks the halls of her old law firm with her client as she prepares to meet with rival attorney Sam Berman. "Your attorney used to be a valued member of our firm. It was a shame to see her go," Berman says before Harry corrects him. "They fired me." Harry represents Earl Connolly, the grieving husband of a woman who died from smoking, and Berman represents the cigarette company being sued. Berman offers a settlement of one $123,000. "For a dead wife?" Harry asks as she quickly rejects the offer. Berman warns Harry that she doesn't want to go to trial; the client's wife freely smoked cigarettes for 35 years, and the company will keep the lawsuit tied up in litigation for years before the case even sees trial. Harry's not afraid of the battle ahead and leaves with her client ready for the litigation war that awaits them.
Harry represents a school principal trying to expel a student with an anxiety-based condition which causes her to have uncontrollable outbursts. In addition, Harry reaches out to Roseanna Remmick for help with a former client who is convinced that his sister was murdered by her husband. Elsewhere, a former high school classmate of Adam's, comes to him for help with her plea bargain on drug and prostitution charges. Tommy prepares for a gala where he hopes to win Trial Lawyer of the Year.
After a police investigation, Harry's next door neighbor is accused of being a sex offender. While the investigation does not yield charges, it becomes grounds for her to lose her job as a teacher and she seeks out Harry's help. Meanwhile, Oliver faces off against opposing counsel, Phoebe Blake, after a couple comes to him to represent their rebellious son who dropped out of school to take a well-paying, full-time job. Back at the office, Adam must play mediator when the women who work downstairs in the shoe store revolt against Chunhua's seemingly tyrannical leadership.
"Now look, Judge. Trials are rarely about the truth. The D.A. distorts, the defense distorts. Why shouldn't the client be allowed to put in her version? After all, it is her life on the line." In order to get her innocent client off, Harry must put her on the stand to testify, but the client has said she plans to lie in order to protect the real culprit. If Harry lets her testify, she'll be suborning perjury, and if she doesn't, her client will surely be convicted, so she must do everything in her power to get her client to tell the truth.
Harry represents a rogue juror who ran away from jury duty in the midst of deliberations on a high-profile murder case. With Tommy's help, Harry must justify the juror's flight which led to a costly mistrial for the State. Elsewhere, Phoebe and Adam defend a reality TV show wife after being sued by her dead husband's family when he commits suicide. Back at the office, Oliver and Cassie strive to balance their newfound relationship with the firm's heavy case-load.
When a hazing ritual goes terribly awry, resulting in 39 members of a school marching band being charged with first degree murder, Harry makes an impassioned plea with the judge to toss out the law and do the right thing. Meanwhile Tommy, Ollie, and Cassie agree to represent a man who claims he was raped by a beautiful woman, and Tommy takes extreme measures to get to the truth.
Series Finale: Harry's ex-husband is found dead and with no one else to claim his body, Harry finds herself planning his funeral which, to her surprise, stirs up old emotions. Meanwhile, she and Tommy agree to represent a man whom police suspect murdered his ex-wife. Elsewhere, Ollie seeks Cassie's help in representing a student who is suing the Law School that rejected her application due to affirmative action quotas and Adam goes up against Phoebe when he represents a man who was fired because he habitually popped his false teeth in and out of his mouth.