Host Bill Nye looks back over the past two centuries, in which chemistry has brought us from a time when atoms were a hypothesis to an age where scientists may be able to combine particles on the atomic level into micro-machines. Learn how electricity transforms chemicals, elements can combine into more complex molecules, and the combination of nonliving substances produced organic compounds that led to pharmacology. Nye examines the second half of the 19th century, a time dominated by discoveries relating to light, electrons, radioactivity, and the periodic table of the elements as well as 20th century advances in science.