After treating an indigent patient against hospital policy, Robin and Patrick have been assigned the night shift at General Hospital. An accidental shooting sends Jason and Spinelli to the hospital. Patrick is injured in an explosion and admitted to General Hospital as a patient. Maxie and Coop are caught in a compromising position and Robin is inspired by a pregnant patient.
Jason learns valuable lessons from Toussaint; Epiphany is upset by the news that her son is a catalyst for a strike; Russell laments a recent streak of bad luck at the hospital; and Leo almost commits a career-threatening blunder.
Jason spends time with his son when Elizabeth is needed in surgery; Patrick confronts his past while treating a troubled teen; Stan changes his opinion of Toussaint; Cody goes to extremes to get his medication; Andy's methods produce dangerous results in the operating room.
A patient's death attracts the unwanted attention of the police; Stan takes the lead in a strike by hospital workers; revelations about Toussaint's past prompt an outburst from Epiphany; Stacey's difficult pregnancy hits home for Robin and Patrick.
Kelly draws Pablo's ire; Patrick and Robin are surprised by the change in a patient's condition; Maxie's infection takes a turn for the worse; and Andy is dubious of a patient's illness.
Stacey gets trapped in an elevator on her way to an emergency C-section, and Stan and Toussaint scramble to repair it. Elsewhere, Leyla's decision has different consequences for two patients.
The staff reacts to the fate of Stacey and her baby; Toussaint makes a shocking discovery about the cause of the elevator jam; Patrick helps Leo with a trauma case.
The staff is preoccupied with the recent string of nefarious deeds; Patrick struggles to support Robin in her hour of need; Maxie's condition brings up bad memories for Leo; Russell tries to keep the hospital running amid rumors of a possible takeover; Epiphany holds on to a mysterious package.
Insurance complications may prevent a necessary surgery for Lainey's father; Robin makes progress in her efforts to adopt Stacey's baby; Toussaint's mysterious past is disclosed by Epiphany; Jolene plots her next move.
Robin faces a new obstacle in her plans to adopt Stacey's baby; Lovell suggests that Jolene's next victim be a doctor; Regina's low self-esteem begins to interfere with her work.
Andy and Kelly desperately try to counsel one another on their addictions; Lainey struggles to deal with her father's condition; Patrick comes clean about his fling with Leyla to Robin, who must face up to the fact that Stacey's daughter is going home with the baby's father; Toussaint learns the results of his latest test.
A police investigation into the death of Lainey's father yields an unlikely suspect; Epiphany surprises Toussaint with some unexpected visitors before his difficult surgery; Lovell urges Jolene to find another victim; the clandestine romance between Patrick and Leyla continues.
In the first-season finale, Spinelli's sleuthing abilities help Jason stop Jolene from completing her final assignment. Meanwhile, a gunfight erupts in the ER between rival gangs, putting the staff and patients in mortal danger.
In the second season premiere, a car crashes into the ER with fatal results and expectant parents Dr. Patrick Drake and Dr. Robin Scorpio are at odds. New interns Claire and Kyle deal with the unpleasant Dr. Leo Julian, and Jagger Cates returns to Port Charles with his son Stone.
Robin uncovers more than she bargains for as she helps a sick child. She soon clashes with Jagger over Stone's unusual behavior as the source of Leo and Kyle's conflict is revealed.
A new trauma patient turns out to be Robin's father Robert Scorpio. Claire and Kyle disagree about their living arrangements as Leo and Saira dance around their attraction, while Epiphany and Toussaint discuss their relationship.
Leo and Kyle's mother appears to visit her sons as Claire's secret eats at her.
A comatose and dying Robert envisions a visit by old friends and loved ones as he loses his will to live.
In an episode Michael Logan of TV Guide says "ends with some mature, uneasy twists,"[14] the aftermath of the explosion outside the hospital plays out as Robert's fate is revealed.