Introduction and theme song
The Bubbler kidnaps the Shah of Shish-Ka-Bob and it's up to the Impossibles to rescue the Shah.
Dr. Shock uses his Master Mix Monster Machine to turn his assistant Igor into an electricity-absorbing monster.
The Spinner steals a $1,000,000 tiara.
The Paper Doll Man has stolen a top secret plan and is out to steal the second part.
Professor Conroy and Buzz unveil the blueprints for the Spy Detector XK-00-7 at a Maximum Security Building. Unfortunately, the blueprints are targeted by Spyder Man.
Beamatron steals a priceless painting from a ship.
The Burrower uses his burrowing machine to steal half a million dollars from the bank and dig ten mile down to his lair.
Upon an encounter with Buzz at the wax museum, Mr. Menace uses his monsters Gadzonka, Gorillis, and Cyclaws in an attack upon San Francisco.
Timeatron uses his powers to bring villains from the past to pillage for him
Smogula freezes the Impossibles and seals them within a cave, so they won't interfere with his plans to conquer Empire City.
A giant alien brain arrives on Earth and captures Buzz and Professor Conroy.
The Speck uses a formula to shrink himself in order to photograph some top secret plans.
To get the Impossibles out of the way, Fero uses his fiddle to transport them to different planets.
Mother Gruesome invents a machine that brings villainous storybook characters out of their stories to help her with her crimes Help Coil Man save way.
Televisatron uses his powers to transport the Impossibles to different television shows Coily and Multi at Fluid Man save it!
Unidentified Fiendish Object The alien Zargon unleashes his warrior Destructo in his plans to conquer Earth.
The Dauber uses a special brush where anything he paints becomes real.
Aquator has stolen a secret formula and shrinks himself to microscopic size.
Plant Man thaws the last three prehistoric plant creatures (consisting of Carnivorous Chewer, Creeping Crusher, and Fire-Breathing Snapdragon) from a glacier and then sprays them with his Obedience Ray in a plot to eliminate Buzz and Frankenstein Jr.
Professor Stretch is causing havoc with his elastical abilities.
The Devilish Dragster has stolen a very valuable item.
Living Images The Mad Inventor has invented the Double Identity Duplicator Projector to make copies of whatever pictures he inserts in it.
The Spinner returns and steals a priceless pooch.
The Satanic Surfer takes pictures of a top secret submarine.
Junk Man creates the Colossal Junk Monster in a plot to eliminate Frankenstein Jr.
The Puzzler steals some top secret documents which he plans to sell to the highest bidder.
Spraysol is out to steal some top secret documents.
Buzz and Frankenstein Jr. guard the Navy's new Hydrotomic Submarine to prevent Dr. Hook and his aquatic monsters from stealing it.
The Sculptor is turning people into statues.
The Artful Archer steals a priceless violin and a million dollars. It's up to the Impossibles to reclaim them.
Zorbo the Great creates a genie and plans to use its three wishes in order to defeat Frankenstein Jr. and conquer the world.
The Inflator creates giant balloon monsters to help him commit crimes.
The Diamond Dazzler has stolen a precious diamond in order to awaken the genie within.
Birdman and his robotic birds Vulturo, Rodantus, and King Condor abduct two astronauts and holds them for a ransom of $1,000,000.
The Paper Doll Man returns and causes trouble for the Impossibles.
Cronella Critch has robbed a charity for orphans party.
Sertano the Satellite King, an alien from Galaxy X, uses a gravity ray in order to get Earth to surrender. Buzz and Frankenstein Jr. must defeat Sertano's robots in order to defeat him.
The Twister is on a crime spree and is stealing precious jewels.
Professor Stretch returns and creates a rubber monster to help him in his crimes.
Manchurian Menace steals a space camera capsule that has just returned with photos from Mars.
The Tapper is a criminal who can transmit himself over the phone lines. He uses this ability to commit crimes.
The Angler has stolen some secret space research and plans to sell them to another country.
To perform a crime wave in London, Baron Von Ghoul creates robotic versions of horror movie monsters Electroflying Firefly, Menacing Mummy and the Wicked Werewolf.
The Ringmaster puts on a circus and robs from those who attend.
Billy the Kidder, a cowboy that rides a robotic horse, is planning to rob the U.S. Mint.
The Mad Inventor has invented the Monstermobile and uses its many gadgets to commit crimes.
The Impossibles fight Doctor Futuro who has come from the fortieth century to their time to steal a million dollar gold brick.
The Clutcher uses an invention that brings his gloves to life.
Mr. Menace uses his putty monster to steal a $1,000,000 coin collection and even kidnaps Buzz. It is up to Frankenstein Jr. to rescue Buzz and defeat Mr. Menace.
Mr. Instant uses his insta-gun, which can make anything in an instant to help him commit crimes.
The Batter kidnaps a baseball star and holds him for a ransom of $1,000,000.
Dr. Spectro creates three giant ghoulish ghosts in order to take over Penciltrainia.
Mr. Ice and his assistant Freeze are freezing the city in order to take over it.
