Chen Chang Sheng's blood can cure all ailments in other people but limits his life expectancy to 20 years. So, he left his master to pursue the only way to extend his life: Pass Zhou Dynasty's "Examination of Dachao" and be admitted to the shrine where a holy stone that supposedly can change a person's destiny is worshipped. He overcame many obstacles, including his inability to practice ascension, to obtain the qualification to enter the exam. Along the way, he befriended a human technology prodigy, a goblin princess and a goblin warrior who assisted him in defeating other contenders. His mission to change his destiny tipped the balance of good and evil. With the help of his betroth, he learned to harness his new powers and save the human world from the demons.
太初元年，有神石從天而降，四散人間。傳說得觀神石碑文者可知天機。神石自此成為人間聖物，天下因此紛亂久矣。直至人族聯合西域妖族，將魔族驅趕到極地草原，方始承平。
少年陳長生（鹿晗飾）身世神秘，在襁褓之中被師父計道人從黃金巨龍口中救下，收為關門弟子。十數年里傳授道書三千卷。然而陳長生體質特異，無法修行，命數活不過二十歲。十多歲的陳長生出師下山，要去周朝神都奪取“大朝試”的頭名以得觀神石，逆天改命。
風從虎，雲從龍。因緣際會與自身努力，陳長生抵擋住了種種勢力的打壓，邁過修行關隘，實力一日千里。也結識了少年天才唐三十六、妖族公主白落衡、妖族武將軒轅破這些摯友，在他們的幫助下，在強手如林的“大朝試”中拔得頭籌。進入神石碑陵後，一夜觀盡陵前碑，引得天象震動。然而一切卻只是開始，隨著天下格局的變動，陳長生不得不捲入其中。
Âgé de 14 ans, Chen Chang Sheng est un orphelin qui a été sauvé par un maître taoïste. Son sang pouvant guérir les maux dont souffrent les autres le destine aussi à mourir à l'âge de 20 ans.
Il fera alors tout pour changer son destin. Il quitte son maître et part à la recherche d'une pierre permettant de changer le destin des gens. Il rencontrera alors des amis et des ennemis et afin d'atteindre son but, il devra faire face à de nombreux obstacles.
